Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• LINE-1 Locus Transcription Nucleates Oncogenic Chromatin Architecture.

  PMID 41489510 · PMC13040219 · Cancer discovery · 2026 · 8 claims · 8 setups

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  LINE-1 RNAs are primarily chromatin-associated nascent transcripts rather than cytosolic mRNAs

  mcf7 cancer qrt-pcr single-molecule chirp-seq

• CTCF/cohesin-binding sites are susceptible to replication-associated DNA damage and genomic instability in cancer cells.

  PMID 41630911 · PMC12860730 · iScience · 2026 · 8 claims · 8 setups

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  CTCF and cohesin (RAD21) remain co-bound to DNA throughout interphase, including during the S (replication) phase, in HeLa cells

  hela tumors flow chromatin frap

• iTRAQ-based proteomics profiling reveals increased metabolic activity and cellular cross-talk in angiogenic compared with invasive glioblastoma phenotype.

  PMID 19674965 · PMC2773724 · Molecular & cellular proteomics : MCP · 2009 · 6 claims · 5 setups

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  Serial transplantation of human GBM xenografts in nude rats converts an initially highly infiltrative, non-angiogenic phenotype into a highly angiogenic phenotype over 4-6 generations.

  membrane-enriched xenograft homogenate quantified itraq western bradford