Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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A novel deep learning-driven framework for improving lncRNA comprehensive annotation with LncADeep 2.0.
PMID 41923359 · PMC13090826 · Bioinformatics (Oxford, England) · 2026 · 8 claims · 8 setups
LncADeep 2.0 outperforms LncADeep and other existing tools for lncRNA identification on both GENCODE annotated transcripts and independent RNA-seq data
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Has reproduction · 86
Screening of core genes prognostic for sepsis and construction of a ceRNA regulatory network.
PMID 36855106 · PMC9976425 · BMC medical genomics · 2023 · 8 claims · 7 setups
RNA-seq of peripheral blood from 23 sepsis patients and 10 healthy controls identifies 1,044 DEmRNAs, 66 DEmiRNAs and 155 DElncRNAs.
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Cell type-specific epigenetic regulatory circuitry of coronary artery disease loci.
PMID 41807385 · PMC12979833 · Nature communications · 2026 · 8 claims · 8 setups
Integration of CAD GWAS summary statistics with epigenetic data from 45 cell types identifies 1580 candidate CAD genes
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Integrated transcriptome and single-cell sequencing analysis identify blood-pancreas shared lncRNA biomarkers in new-onset T2DM.
PMID 41915667 · PMC13037964 · PloS one · 2026 · 8 claims · 6 setups
1,709 lncRNAs are differentially expressed in peripheral blood of new-onset T2DM patients vs controls
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Has reproduction · 83
Discovery and validation of molecular patterns and immune characteristics in the peripheral blood of ischemic stroke patients.
PMID 38650649 · PMC11034498 · PeerJ · 2024 · 8 claims · 8 setups
188 differentially expressed genes (DEGs) between IS and control blood samples were identified and enriched in immune-related biological pathways
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CRESCENT, a comprehensive RNA-Seq expression, splicing, and coding/non-coding element network tool.
PMID 41566196 · PMC12895761 · BMC bioinformatics · 2026 · 6 claims · 6 setups
CRESCENT is a Snakemake workflow performing fully automated, comprehensive RNA-Seq analysis integrating differential expression, differential alternative splicing (DAS), differential transcript usage (DTU), and GO enrichment
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Has reproduction · 85
Integration of multi-omics and machine learning strategies identifies immune related candidate biomarkers in inflammation-associated hypertrophic cardiomyopathy.
PMID 41080564 · PMC12510942 · Frontiers in immunology · 2025 · 8 claims · 8 setups
Seven key immune-related genes (RNF165, SNCA, SRGN, MARCO, STEAP4, SIGLEC9, TKT) are associated with HCM by intersecting DEGs with MR-identified eQTLs
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Molecular signatures of cell diversity modulated by long noncoding RNAs in the human fetal spinal cord.
PMID 42006319 · PMC13090696 · iScience · 2026 · 8 claims · 7 setups
Three neural stem cell (NSC) lineages (NSC1, NSC2, NSCs) were annotated in the human fetal spinal cord