Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• The origins of lactase persistence in Europe.

  PMID 19714206 · PMC2722739 · PLoS computational biology · 2009 · 8 claims · 5 setups

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  The −13,910*T allele first underwent selection among dairying farmers around 7,500 years ago in a region between the central Balkans and central Europe, possibly linked to the Linearbandkeramik culture.

  simulated simulation 910*t farming demic approximate comparison

• Agent-based modeling of cellular dynamics in adoptive cell therapy.

  PMID 41673469 · PMC13004971 · Communications biology · 2026 · 7 claims · 7 setups

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  ABMACT, an agent-based model of adoptive cell therapy, recapitulated cellular dynamics in two cancer preclinical models (lymphoma and glioblastoma mouse models).

  xenograft il-15-armored cord shanley scrna-seq autonomous rechallenge

• Contributions from molecular/biochemical approaches in epidemiology to cancer risk assessment and prevention.

  PMID 1486845 · PMC1519598 · Environmental health perspectives · 1992 · 8 claims · 8 setups

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  Genotoxicity of chemicals is a continuous, graded property (agent score) rather than a simple dichotomy of mutagenic vs. nonmutagenic chemicals

  chemical drosophila normal uv-sensitive short-term drosophila excision

• Functional epigenomics approach to identify methylated candidate tumour suppressor genes in renal cell carcinoma.

  PMID 18195710 · PMC2361461 · British journal of cancer · 2008 · 8 claims · 4 setups

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  HAI-2/SPINT2 was previously identified as a novel epigenetically inactivated candidate RCC tumour suppressor gene

  rcc skrc39 gene rt-pcr bisulphite

• A mechanistic model captures the emergence and implications of non-genetic heterogeneity and reversible drug resistance in ER+ breast cancer cells.

  PMID 34316714 · PMC8271219 · NAR cancer · 2021 · 7 claims · 8 setups

  Has reproduction · 85

  EMT and tamoxifen-resistance (TamR) regulatory axes can drive one another, enabling non-genetic heterogeneity via six co-existing phenotypes (ES, ER, HS, HR, MS, MR)

  gene same randomized publicly racipe stochastic randomized

• Olden times: looking back on a career at the NIEHS.

  PMID 15289171 · PMC1247486 · Environmental health perspectives · 2004 · 8 claims · 3 setups

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  Kenneth Olden served 13 years as director of NIEHS and the National Toxicology Program, the first African American to head an NIH institute

  environmentally genome gene microarray transgenic

• Glucocorticoid resistance in a multiple myeloma cell line is regulated by a transcription elongation block in the glucocorticoid receptor gene (NR3C1).

  PMID 19133980 · PMC4303606 · British journal of haematology · 2009 · 7 claims · 6 setups

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  Downregulation of GR mRNA in the resistant myeloma cell line is caused by a block to transcriptional elongation within intron B of the GR gene

  mm.1s pcr demethylating quantitative

• CCAAT-enhancer binding protein delta functions as a tumor suppressor gene in acute myeloid leukemia.

  PMID 41844049 · PMC13010944 · Neoplasia (New York, N.Y.) · 2026 · 8 claims · 8 setups

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  CEBPD is identified as a novel tumor suppressor gene in AML

  paired aml tcga oci-aml5 bulk bart kaplan-meier

• Emerging strategies and applications of pharmacogenomics.

  PMID 15606999 · PMC3500198 · Human genomics · 2004 · 7 claims · 7 setups

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  Effective pharmacogenomics requires infrastructure including informed consent processes, accurate phenotypic data collection, high-throughput genotyping technology, and integrated information technology systems.

  subjects ethnically patients genome-wide gene case-control

• FOXM1 inhibitor, RCM‑1, enhances venetoclax mediated apoptosis through downregulation of ATP2B4 in rhabdomyosarcoma.

  PMID 41789627 · PMC12987556 · International journal of oncology · 2026 · 8 claims · 8 setups

  Has reproduction · 10

  Combination therapy of RCM-1 and venetoclax inhibits RMS tumor growth more efficiently than venetoclax alone in an animal model by decreasing proliferation and inducing apoptosis

  rms injected muscle cck-8 caspase subcutaneous

• Stress testing reveals selective vulnerabilities in protein homeostasis.

  PMID 41575849 · PMC13040462 · Cell reports · 2026 · 8 claims · 8 setups

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  Tn-seq fitness profiling across strains lacking major chaperones/proteases under proteotoxic stress reveals stress- and strain-specific fitness determinants otherwise masked by redundancy

  caulobacter transposon growth sequencing