Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Stabilizing mutation of CTNNB1/beta-catenin and protein accumulation analyzed in a large series of parathyroid tumors of Swedish patients.

  PMID 18541010 · PMC2435117 · Molecular cancer · 2008 · 8 claims · 5 setups

  Full-text index only

  The CTNNB1 stabilizing mutation S37A was detected in 6 of 104 (5.8%) sporadic parathyroid adenomas by direct DNA sequencing.

  sporadic ctnnb1 paired frozen direct restriction snp

• Single-cell transcriptional dynamics of flavivirus infection.

  PMID 29451494 · PMC5826272 · eLife · 2018 · 8 claims · 6 setups

  Has reproduction · 90

  viscRNA-Seq simultaneously quantifies whole single-cell host transcriptome and intracellular viral RNA from the same cell, including non-polyadenylated viruses via a virus-specific oligo

  hepatoma single huh7 denv-infected single-cell qpcr loss-of-function

• Stromal androgen signaling acts as tumor niches to drive prostatic basal epithelial progenitor-initiated oncogenesis.

  PMID 36323713 · PMC9630272 · Nature communications · 2022 · 7 claims · 7 setups

  Has reproduction · 63

  Loss of AR in stromal Gli1-lineage cells diminishes prostate epithelial oncogenesis and tumor development.

  ugm hi-myc prostate hmyctg+ genetic single-cell gene

• Proteomic analysis of tumor necrosis factor-alpha resistant human breast cancer cells reveals a MEK5/Erk5-mediated epithelial-mesenchymal transition phenotype.

  PMID 19087274 · PMC2656902 · Breast cancer research : BCR · 2008 · 8 claims · 7 setups

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  MEK5 over-expression promotes a TNF-α resistance phenotype in MCF-7 breast cancer cells

  mcf-7-mek5 mcf-7 western clonogenic immunofluorescence