Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 76
Intrinsic suppression of type I interferon production underlies the therapeutic efficacy of IL-15-producing natural killer cells in B-cell acute lymphoblastic leukemia.
PMID 37217248 · PMC10231005 · Journal for immunotherapy of cancer · 2023 · 8 claims · 8 setups
High expression of IFN-I signaling/response genes (IFNAR1, IFNAR2, STAT1, MX1, OAS1) predicts favorable relapse-free survival in B-ALL patients
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Clonal dynamics shaped by diverse drug-tolerant persister states in melanoma resistance.
PMID 41776501 · PMC13162433 · Molecular cancer · 2026 · 8 claims · 6 setups
MeRLin, a single-vector high-complexity lineage tracing platform integrating cellular barcoding, scRNA-seq, RNA-FISH, and computational analysis, was developed to track clonal and transcriptional dynamics in a melanoma PDX model
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Engineering NK and T cells with metabolite-sensing receptors to target solid tumors.
PMID 41872506 · PMC13132725 · Nature immunology · 2026 · 8 claims · 8 setups
GPR183, GPR84, GPR34 and GPR18 were identified as top enhancers of NK cell tumor infiltration and chemotaxis to breast and ovarian cancer via CRISPRa screens
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Patient-derived orthotopic xenograft models recapitulate the peritoneal dissemination of pancreatic cancer and delineate its transcriptional and regulatory programs.
PMID 41673768 · PMC12998334 · Journal of experimental & clinical cancer research : CR · 2026 · 6 claims · 8 setups
Organoids derived from malignant effusions of PDAC patients reproducibly generate peritoneal metastases after orthotopic implantation into the pancreas of immunodeficient mice
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X-linked cancer-associated polypeptide (XCP) from lncRNA1456 modulates PHF8 histone demethylase activity to regulate the epigenome, gene expression, and cellular pathways in breast cancer.
PMID 41922576 · PMC13099652 · Oncogene · 2026 · 8 claims · 8 setups
lncRNA1456, previously classified as noncoding, encodes a 132 amino acid protein named XCP (X-linked Cancer-associated Polypeptide)
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Therapeutic synergies that overcome carboplatin resistance in triple-negative breast cancer.
PMID 41630032 · PMC13037280 · Journal of experimental & clinical cancer research : CR · 2026 · 8 claims · 8 setups
Four isogenic carboplatin-resistant (CR) PDX pairs (WHIM30, BCM-2147, BCM-3887, BCM-7482) were generated via serial in vivo carboplatin exposure to model acquired resistance in TNBC
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Ectopic CD11c Drives SMAD3-Mediated Aberrant Antigen Presentation and Epithelial-Mesenchymal Transition in Esophageal Squamous Cell Carcinoma.
PMID 41799568 · PMC12963642 · Cancer communications (London, England) · 2026 · 8 claims · 13 setups
An ESCC epithelial cell subcluster with ectopic CD11c (ITGAX) expression, found in both mice and humans, exhibits concurrent impaired antigen presentation and EMT phenotypes
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An artificial intelligence optimized hepatic differentiation unveils NR5A2 and AP-1 transcriptional regulation in hepatic maturation.
PMID 41962865 · PMC13185932 · The Journal of biological chemistry · 2026 · 7 claims · 8 setups
A CNN-based AI algorithm trained on bright-field images of hepatic progenitor cells (HPCs) accurately predicts successful vs. failed differentiation without immunostaining or lineage tracing