Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Robust transcriptomic hallmarks targeting intratumor heterogeneity in intrahepatic cholangiocarcinoma.
PMID 41916296 · PMC13130669 · Cell reports. Medicine · 2026 · 8 claims · 8 setups
Immune and stromal heterogeneity, rather than genetic variation, are primary drivers of gene expression ITH in iCCA
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Has reproduction · 88
AuPairWise: A Method to Estimate RNA-Seq Replicability through Co-expression.
PMID 27082953 · PMC4833304 · PLoS computational biology · 2016 · 7 claims · 6 setups
Sample-sample correlation of transcript abundances is a misleading measure of replicability for assessing differential expression, because it is dominated by gene-specific dynamic ranges rather than condition-dependent variation.
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Has reproduction · 56
DESE: estimating driver tissues by selective expression of genes associated with complex diseases or traits.
PMID 31694669 · PMC6836538 · Genome biology · 2019 · 8 claims · 8 setups
DESE is a unified iterative framework that estimates driver tissues of complex diseases/traits from tissue-selective expression of GWAS-associated genes, and outputs prioritized susceptibility genes as a byproduct
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Annotation-free prediction of immunotherapy response in melanoma using single-cell transcriptomic data.
PMID 41758825 · PMC12948085 · PloS one · 2026 · 8 claims · 6 setups
AI-based predictive models built on unannotated scRNA-seq data (cell-by-gene expression matrices) can classify melanoma patients as ICI responders vs. non-responders