Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Insights from pooled CRISPRi single-cell screens in K562 cells reveal gene functions, regulatory networks, and highlight opportunities and limitations.
PMID 41826830 · PMC13097927 · BMC genomics · 2026 · 7 claims · 7 setups
A modified CROP-seq-CRISPRi protocol allows direct capture of sgRNAs from the cDNA library without a separate enrichment step, improving sgRNA assignment per cell
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Transcriptomic and phenotypic convergence of neurodevelopmental disorder risk genes in vitro and in vivo.
PMID 42032432 · PMC13156037 · Nature neuroscience · 2026 · 6 claims · 6 setups
Transcriptomic convergence following NDD gene knockout is highly cell-type-specific and strongest in mature glutamatergic neurons (iGLUTs)
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Pre-existing cell states predict resistance to multiple treatments.
PMID 41916275 · PMC13261651 · Cell genomics · 2026 · 8 claims · 5 setups
Rare melanoma clones can develop resistance to multiple diverse treatments simultaneously, not just single treatments
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Single-Cell Lineage Tracing Uncovers Resistance Signatures and Sensitizing Strategies to FLT3 Inhibitors in Acute Myeloid Leukemia.
PMID 41270153 · PMC7618455 · Cancer research · 2026 · 8 claims · 8 setups
ReSisTrace single-cell lineage tracing identifies pre-resistant and pre-sensitive cell states to FLT3 inhibitors midostaurin and quizartinib in FLT3-ITD-positive MOLM-13 AML cells before treatment