Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 6

System / cell line: test ✕ Assay: gene-signature ✕ Clear

Comparative analysis of molecular signatures reveals a hybrid approach in breast cancer: Combining the Nottingham Prognostic Index with gene expressions into a hybrid signature.

PMID 35143511 · PMC8830616 · PloS one · 2022 · 8 claims · 6 setups

Has reproduction · 48

A Hybrid signature combining the NPI with 14 SIS-selected genes was constructed from METABRIC training data

metabric gse96058 test gene sure cox
Reverse Engineering of the Pediatric Sepsis Regulatory Network and Identification of Master Regulators.

PMID 34680414 · PMC8533457 · Biomedicines · 2021 · 7 claims · 8 setups

Has reproduction · 67

A set of 15 TFs was identified as sepsis-specific master regulators of pediatric sepsis, dividing into two non-overlapping clusters.

blood cd4+ pbmc regulons microarray differential master
A taxonomy of epithelial human cancer and their metastases.

PMID 20017941 · PMC2806369 · BMC medical genomics · 2009 · 8 claims · 6 setups

Full-text index only

Unsupervised hierarchical clustering of 1566 primary epithelial tumors yields large tissue-enriched clusters (breast, colon/GI, lung, ovary, kidney) plus smaller prostate, thyroid-kidney, and mixed clusters

epithelial tumor metastatic breast microarray gene fisher
Gene signature discovery and systematic validation across diverse clinical cohorts for TB prognosis and response to treatment.

PMID 37471455 · PMC10393163 · PLoS computational biology · 2023 · 8 claims · 7 setups

Has reproduction · 100

A network-based meta-analysis of 27 discovery cohorts identified a common 45-gene signature specific to active TB disease across studies.

blood aggregated 45-gene independent bulk network-based gene
Construction and Validation of an Immune Infiltration-Related Gene Signature for the Prediction of Prognosis and Therapeutic Response in Breast Cancer.

PMID 33986754 · PMC8110914 · Frontiers in immunology · 2021 · 7 claims · 8 setups

Has reproduction · 51

A higher immune infiltration-related risk score (IRS) indicates worse prognosis and lower sensitivity to immunotherapy in breast cancer patients

tcga candidate cancer univariate weighted lasso
Differential Infiltration of Key Immune T-Cell Populations Across Malignancies Varying by Immunogenic Potential and the Likelihood of Response to Immunotherapy.

PMID 39682743 · PMC11640164 · Cells · 2024 · 8 claims · 5 setups

Has reproduction

Estimated T-cell infiltration differs significantly across melanoma, bladder, ovarian, and pancreatic cancers, tracking known immunogenic potential.

tumor melanoma orien bulk gene kaplan-meier

Experiments

Comparative analysis of molecular signatures reveals a hybrid approach in breast cancer: Combining the Nottingham Prognostic Index with gene expressions into a hybrid signature.

Reverse Engineering of the Pediatric Sepsis Regulatory Network and Identification of Master Regulators.

A taxonomy of epithelial human cancer and their metastases.

Gene signature discovery and systematic validation across diverse clinical cohorts for TB prognosis and response to treatment.

Construction and Validation of an Immune Infiltration-Related Gene Signature for the Prediction of Prognosis and Therapeutic Response in Breast Cancer.

Differential Infiltration of Key Immune T-Cell Populations Across Malignancies Varying by Immunogenic Potential and the Likelihood of Response to Immunotherapy.