Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 91
Lineage commitment of dermal fibroblast progenitors is controlled by Kdm6b-mediated chromatin demethylation.
PMID 37602956 · PMC10548174 · The EMBO journal · 2023 · 6 claims · 5 setups
E14.5 DFPs have a repressed transcriptional profile marked by high H3K27me3 and inaccessible chromatin at lineage-specific genes
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Has reproduction · 50
DNA Methylation Directs Polycomb-Dependent 3D Genome Re-organization in Naive Pluripotency.
PMID 31722211 · PMC6856714 · Cell reports · 2019 · 7 claims · 6 setups
The altered 3D genome of 2i-cultured ESCs (chromatin decompaction and loss of polycomb interactions at polycomb targets) is due to redistribution of polycomb away from its targets.