Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Antibody binding loop insertions as diversity elements.
PMID 17023486 · PMC1635297 · Nucleic acids research · 2006 · 7 claims · 8 setups
A lysozyme-binding VHH CDR3 loop can be grafted into two surface-exposed loops of superfolder GFP, conferring lysozyme-binding activity while the protein remains fluorescent.
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A focused antibody library for selecting scFvs expressed at high levels in the cytoplasm.
PMID 18034894 · PMC2241821 · BMC biotechnology · 2007 · 7 claims · 7 setups
A human scFv library was built on the single scFv13R4 framework with CDR3 loops diversified to mimic natural human CDR3 amino-acid distributions.
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Has reproduction · 95
Pathway-targeting gene matrix for Drosophila gene set enrichment analysis.
PMID 34710184 · PMC8553153 · PloS one · 2021 · 8 claims · 4 setups
Gene matrix files for GSEA are largely unavailable for Drosophila, limiting pathway-level enrichment analysis in this model organism
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Paircomp, FamilyRelationsII and Cartwheel: tools for interspecific sequence comparison.
PMID 15790396 · PMC1087472 · BMC bioinformatics · 2005 · 8 claims · 7 setups
Paircomp, FamilyRelationsII, and Cartwheel together form an integrated system for comparing, viewing, and managing analyses of BAC-sized (~100 kb) genomic sequence pairs.
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Integrated proteomic and transcriptomic profiling of mouse lung development and Nmyc target genes.
PMID 17486137 · PMC2673710 · Molecular systems biology · 2007 · 8 claims · 7 setups
Global MudPIT-based proteomic profiling across six mouse lung developmental time points (E13.5–P56) identifies thousands of proteins and captures developmental/cell-biological expression patterns.
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Identification of the REST regulon reveals extensive transposable element-mediated binding site duplication.
PMID 16899447 · PMC1557810 · Nucleic acids research · 2006 · 8 claims · 8 setups
The RE1 PSSM identifies functional RE1 binding sites with greater sensitivity and selectivity than the previously used RE1 consensus sequence
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Proteomic analysis of differential proteins in pancreatic carcinomas: Effects of MBD1 knock-down by stable RNA interference.
PMID 18445260 · PMC2386481 · BMC cancer · 2008 · 8 claims · 5 setups
Stable RNAi-mediated MBD1 knock-down was successfully established in the BxPC-3 pancreatic cancer cell line using a recombinant siRNA plasmid