Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Shaken not stirred: a global research cocktail served in Hinxton.
PMID 18036269 · PMC2258181 · Genome biology · 2007 · 8 claims · 8 setups
Network-guided reverse genetics using probabilistic functional gene networks (e.g. YeastNet, WormNet) reduces the search space for identifying genes in a given biological process
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Has reproduction · 100
The liver as an immunological barrier redefined by single-cell analysis.
PMID 32176810 · PMC7218664 · Immunology · 2020 · 8 claims · 8 setups
Emerging single-cell technologies have advanced or redefined understanding of the liver's immunological barrier function
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Large-scale discovery and validation of functional elements in the human genome.
PMID 15774039 · PMC1088940 · Genome biology · 2005 · 8 claims · 8 setups
Genome-wide tiling microarray hybridization reveals large, diverse sets of transcripts, many of which lack existing gene annotations
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Has reproduction · 48
Irisin ameliorates obesity and insulin resistance via adipose tissue IL-33 and regulatory T cells.
PMID 41933175 · PMC13052164 · Nature metabolism · 2026 · 8 claims · 8 setups
Irisin modulates adipose tissue inflammation by increasing IL-33 production and preserving ST2+ regulatory T cells in white adipose tissues, thereby improving obesity and glucose intolerance.
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Proteomic analysis of the mammalian nuclear pore complex.
PMID 12196509 · PMC2173148 · The Journal of cell biology · 2002 · 8 claims · 7 setups
Mass spectrometry was used to identify all proteins present in a biochemically purified rat liver NPC fraction.
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MitoP2: the mitochondrial proteome database--now including mouse data.
PMID 16381964 · PMC1347489 · Nucleic acids research · 2006 · 8 claims · 8 setups
MitoP2 is a database integrating manually annotated mitochondrial reference proteins, functions, and disease associations for yeast, human, and mouse, with cross-species orthologue mapping
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Has reproduction · 97
Exosomal microRNA miR-92a concentration in serum reflects human brown fat activity.
PMID 27117818 · PMC4853423 · Nature communications · 2016 · 8 claims · 8 setups
Brown and beige adipocytes release exosomes, and thermogenic activation increases exosome release both in vitro and in vivo.
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An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer.
PMID 19012953 · PMC2990916 · Cell · 2008 · 7 claims · 8 setups
shRNA pools targeting genes recurrently deleted in human HCC accelerate hepatocarcinogenesis in vivo, whereas randomly selected shRNA pools do not.
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Human Proteinpedia: a unified discovery resource for proteomics research.
PMID 18948298 · PMC2686511 · Nucleic acids research · 2009 · 8 claims · 8 setups
Human Proteinpedia is a community portal using a distributed annotation system (DAS) to share both published and unpublished human proteomic data
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Enthoprotin: a novel clathrin-associated protein identified through subcellular proteomics.
PMID 12213833 · PMC2173151 · The Journal of cell biology · 2002 · 8 claims · 8 setups
Subcellular proteomics of purified CCVs identifies enthoprotin (encoded by KIAA0171), a novel ENTH domain-containing protein not previously detected at the protein level.
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Has reproduction · 73
FRMD8 inhibits tumor metastasis in BRCA1-associated TNBC by negatively regulating tmTNF-α.
PMID 40619383 · PMC12229025 · Cellular & molecular biology letters · 2025 · 8 claims · 8 setups
Low FRMD8 expression in BRCA1-mutant breast cancer cells significantly enhances metastatic potential to various organs