Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Addressing pandemic-wide systematic errors in the SARS-CoV-2 phylogeny.
PMID 41663577 · PMC12982125 · Nature methods · 2026 · 6 claims · 3 setups
Most SARS-CoV-2 genomes were sequenced using tiled amplicon methods, which introduce systematic errors unless assembly software is aware of the amplicon scheme and the error modes of amplicon sequencing
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SW-ARRAY: a dynamic programming solution for the identification of copy-number changes in genomic DNA using array comparative genome hybridization data.
PMID 15961730 · PMC1151590 · Nucleic acids research · 2005 · 7 claims · 5 setups
SW-ARRAY, an adaptation of the Smith-Waterman dynamic programming algorithm, provides a sensitive and robust method for identifying copy-number changes in array CGH data
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FracFixR: a compositional statistical framework for absolute proportion estimation between fractions in RNA sequencing data.
PMID 41264734 · PMC12866640 · Bioinformatics (Oxford, England) · 2026 · 7 claims · 5 setups
FracFixR reconstructs original fraction proportions by modeling the compositional relationship between whole and fractionated RNA samples using non-negative least squares (NNLS) regression on selected transcripts
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HapMap-based study of the 17q21 ERBB2 amplicon in susceptibility to breast cancer.
PMID 17117180 · PMC2360759 · British journal of cancer · 2006 · 6 claims · 5 setups
Common genetic variation (tSNPs and haplotypes) across the 400-kb 17q21 ERBB2 amplicon is not associated with breast cancer risk in British women.
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Has reproduction · 30
Minimal metabolic pathway structure is consistent with associated biomolecular interactions.
PMID 24987116 · PMC4299494 · Molecular systems biology · 2014 · 8 claims · 8 setups
MinSpan, a mixed-integer linear optimization algorithm, computes the shortest, linearly independent pathways (sparsest basis of the null space of the stoichiometric matrix S) for genome-scale metabolic networks, which convex approaches (extreme pathways, elementary flux modes) cannot do at genome scale.
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Has reproduction
Using random walks to identify cancer-associated modules in expression data.
PMID 24128261 · PMC4015830 · BioData mining · 2013 · 8 claims · 8 setups
Walktrap-GM, a random-walk community detection algorithm adapted with stopping criteria (maximum modularity, maximum size, maximum module score), identifies modules significantly enriched with cancer genes in expression-weighted interaction networks.