Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 71
RNAmountAlign: Efficient software for local, global, semiglobal pairwise and multiple RNA sequence/structure alignment.
PMID 31978147 · PMC6980424 · PloS one · 2020 · 8 claims · 6 setups
RNAmountAlign is the first RNA sequence/structure pairwise alignment algorithm based on incremental ensemble mountain distance, running in O(n^3) time and O(n^2) space for two sequences of length n.
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Computation of haplotypes on SNPs subsets: advantage of the "global method".
PMID 17067372 · PMC1636337 · BMC genetics · 2006 · 6 claims · 4 setups
The global method for subhaplotyping always yields a lower error rate than the direct method across datasets and SNP subset sizes
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Comparative gene finding in chicken indicates that we are closing in on the set of multi-exonic widely expressed human genes.
PMID 15809229 · PMC1074396 · Nucleic acids research · 2005 · 8 claims · 6 setups
Comparative gene finding (SGP2) between human and chicken, followed by RT-PCR verification, adds at most ~0.2% new genes to the multi-exonic human gene catalog
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Genomic and bioinformatics analysis of human adenovirus type 37: new insights into corneal tropism.
PMID 18471294 · PMC2397415 · BMC genomics · 2008 · 7 claims · 7 setups
The complete genome of HAdV-37 was sequenced and annotated (35,213 bp, 56.6% GC content, 35 predicted coding sequences plus 8 hypothetical ORFs)
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Having a BLAST with bioinformatics (and avoiding BLASTphemy).
PMID 11597340 · PMC138974 · Genome biology · 2001 · 8 claims · 4 setups
BLAST is the most widely used tool for searching biological sequences for regions of local similarity
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Has reproduction · 44
A Reference DNA Barcode Library for UK Fungi associated with Bark and Ambrosia Beetles.
PMID 41022899 · PMC12480477 · Scientific data · 2025 · 6 claims · 6 setups
A reference DNA barcode library of fungi associated with over 1000 UK bark and ambrosia beetles across 25 native weevil species was generated, resulting in 5274 identified fungal OTUs.
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What makes species unique? The contribution of proteins with obscure features.
PMID 16859532 · PMC1779552 · Genome biology · 2006 · 7 claims · 8 setups
POFs constitute 18-38% (average 26%) of a typical eukaryotic proteome
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Has reproduction · 30
Minimal metabolic pathway structure is consistent with associated biomolecular interactions.
PMID 24987116 · PMC4299494 · Molecular systems biology · 2014 · 8 claims · 8 setups
MinSpan, a mixed-integer linear optimization algorithm, computes the shortest, linearly independent pathways (sparsest basis of the null space of the stoichiometric matrix S) for genome-scale metabolic networks, which convex approaches (extreme pathways, elementary flux modes) cannot do at genome scale.
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Has reproduction · 75
Dynamic reversal of random X-Chromosome inactivation during iPSC reprogramming.
PMID 31515287 · PMC6771397 · Genome research · 2019 · 7 claims · 6 setups
XCR during iPSC reprogramming is hierarchical, with distinct subsets of X-linked genes reactivating early, intermediate, late, and very late