Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Of mice and men: comparative proteomics of bronchoalveolar fluid.
PMID 20032019 · PMC3049194 · The European respiratory journal · 2010 · 8 claims · 8 setups
Comparative shotgun proteomics of human and mouse BALF identifies conserved pathways (immunity, defence response, protease activity) alongside species-specific divergent pathways.
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Application of OMICS technologies in occupational and environmental health research; current status and projections.
PMID 19933307 · PMC2910417 · Occupational and environmental medicine · 2010 · 8 claims · 6 setups
Five OMICS technologies are well established: genotyping, transcriptomics, epigenomics, proteomics, and metabolomics
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Construction of a high-resolution genetic linkage map and comparative genome analysis for the reef-building coral Acropora millepora.
PMID 19900279 · PMC3091320 · Genome biology · 2009 · 8 claims · 6 setups
This is the first genetic linkage map constructed for any coral species or any non-Bilaterian animal
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Involvement of the modifier gene of a human Mendelian disorder in a negative selection process.
PMID 19888326 · PMC2765618 · PloS one · 2009 · 7 claims · 4 setups
The frequency of SAA1 alpha/alpha homozygotes is much higher among Armenian FMF patients (24%) than Karabakhian FMF patients (4%)
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Divergence of exonic splicing elements after gene duplication and the impact on gene structures.
PMID 19883501 · PMC3091315 · Genome biology · 2009 · 8 claims · 7 setups
ESEs and ESSs diverge especially fast shortly after gene duplication, correlating with time since duplication (Ks)
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Sequence variations of GRM6 in patients with high myopia.
PMID 19862333 · PMC2765235 · Molecular vision · 2009 · 7 claims · 8 setups
Three novel GRM6 variations with predicted functional consequences (c.67-82delCAGGCGGGCCTGGCGCinsT, c.858-5a>g, c.1537G>A) were found in high myopia patients but absent in 96 controls
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Toward the use of genomics to study microevolutionary change in bacteria.
PMID 19855823 · PMC2756242 · PLoS genetics · 2009 · 7 claims · 5 setups
The clonal population structure of bacteria, combined with occasional DNA import, provides a powerful context for identifying genetic bases of adaptive phenotypes via association studies.
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Point mutations in GLI3 lead to misregulation of its subcellular localization.
PMID 19829694 · PMC2758996 · PloS one · 2009 · 6 claims · 8 setups
The MID1-α4-PP2A complex regulates the subcellular localization and transcriptional activity of GLI3.
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Reconstructing Indian population history.
PMID 19779445 · PMC2842210 · Nature · 2009 · 8 claims · 8 setups
Most Indian populations descend from a mixture of two ancient, genetically divergent populations: ANI (close to Middle Easterners, Central Asians, Europeans) and ASI (as distinct from ANI and East Asians as those are from each other).
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MtSNPscore: a combined evidence approach for assessing cumulative impact of mitochondrial variations in disease.
PMID 19758471 · PMC2745589 · BMC bioinformatics · 2009 · 8 claims · 5 setups
MtSNPscore, a weighted scoring pipeline combining literature evidence, in silico predictions, and case/control frequency, can prioritize likely pathogenic mtDNA variations
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A statistical model to identify differentially expressed proteins in 2D PAGE gels.
PMID 19763172 · PMC2734266 · PLoS computational biology · 2009 · 7 claims · 5 setups
A mixture likelihood model incorporating both detected and non-detected proteins has higher statistical power to detect differential expression than standard approaches like the Student's t-test.
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CLEAN: CLustering Enrichment ANalysis.
PMID 19640299 · PMC2734555 · BMC bioinformatics · 2009 · 8 claims · 4 setups
The gene-specific CLEAN score improves reproducibility of cluster analysis conclusions across independent datasets compared to the traditional cluster-wide score (cwCLEAN).
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Tracing the early bacterial settlers in preterm and very-low birth-weight infants: first report of microbiota dynamics in South American neonates.
PMID 41563098 · PMC12890024 · Infection and immunity · 2026 · 7 claims · 7 setups
Klebsiella pneumoniae species complex and Escherichia coli dominate the gut microbial composition of VLBW infants
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pmid-41507436
PMID 41507436 · PMC12859067 · 7 claims · 7 setups
scXDR outperforms seven methods that transfer drug response information from bulk RNA-seq to single-cell data, across all four evaluated scenarios
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pmid-41513659
PMID 41513659 · PMC12858858 · 7 claims · 6 setups
sCellST is a weakly supervised (Multiple Instance Learning) deep learning framework that predicts single-cell gene expression from H&E images alone, trained using paired spatial transcriptomics (Visium) and H&E slides
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Peeling off the layers: skin taping and a novel proteomics approach to study atopic dermatitis.
PMID 19748658 · PMC8648281 · The Journal of allergy and clinical immunology · 2009 · 8 claims · 3 setups
Noninvasive D-Squame tape stripping coupled with MS proteomics can profile the AD skin proteome
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scPASU: A computational protocol for quantifying polyadenylation site usage and alternative polyadenylation from 3' scRNA-seq data.
PMID 42085187 · PMC13157062 · STAR protocols · 2026 · 8 claims · 6 setups
scPASU is a Snakemake-based workflow that quantifies APA from standard 3′ scRNA-seq data without requiring specialized library preparation
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Method of regulatory network that can explore protein regulations for disease classification.
PMID 19962281 · PMC7126395 · Artificial intelligence in medicine · 2010 · 6 claims · 2 setups
A regulatory network (RN) can be constructed as a hopfield-like network, with nodes as biomarkers and directed weighted connections as regulatory relationships, optimized by minimizing an energy function measuring input-output disagreement.
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A novel peak detection approach with chemical noise removal using short-time FFT for prOTOF MS data.
PMID 19681055 · PMC2782493 · Proteomics · 2009 · 8 claims · 2 setups
PDA_stFFT is a novel automatic peak detection method for prOTOF MS data that does not require a priori knowledge of protein masses
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Changes in social contacts in England during the COVID-19 pandemic between March 2020 and March 2021 as measured by the CoMix survey: A repeated cross-sectional study.
PMID 35231023 · PMC8887739 · PLoS medicine · 2022 · 8 claims · 2 setups
Recorded social contacts in England decreased dramatically compared to prepandemic levels measured by the POLYMOD study