Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Epigenetic regulation of serine biosynthesis by PHF8 during neurogenesis.
PMID 41714361 · PMC13022353 · EMBO reports · 2026 · 8 claims · 8 setups
PHF8 is required for neural stem cell (NSC) proliferation in vitro
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Multi-omics analysis of interspecies interactions in a soil Streptomyces community provides functional insights into siderophore ecology.
PMID 41942569 · PMC13061897 · Scientific reports · 2026 · 8 claims · 7 setups
Strain A shows pronounced phenotypic growth stimulation (increased colony area, aerial hyphae) when co-cultured with strains B, C, and D, strongest with strain C
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Evolutionarily conserved human targets of adenosine to inosine RNA editing.
PMID 15731336 · PMC549564 · Nucleic acids research · 2005 · 8 claims · 6 setups
Identified four novel human ADAR editing substrates causing amino acid changes: FLNA, BLCAP, CYFIP2 and IGFBP7
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Has reproduction · 98
A data-driven estimation of the ribosome drop-off rate in S. cerevisiae reveals a correlation with the genes length.
PMID 38638702 · PMC11025885 · NAR genomics and bioinformatics · 2024 · 8 claims · 7 setups
Ribosome drop-off events occur at a significant rate in S. cerevisiae cultured in standard conditions
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Mutational landscape and molecular bases of echinocandin resistance in Saccharomyces cerevisiae.
PMID 41766466 · PMC13147539 · Genetics · 2026 · 8 claims · 5 setups
The three echinocandin resistance hotspots of Fks1 form a single, solvent-exposed, water-filled binding cavity spanning hotspot 1, 2, and 3
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Has reproduction · 81
Ribosome A and P sites revealed by length analysis of ribosome profiling data.
PMID 25805170 · PMC4402525 · Nucleic acids research · 2015 · 7 claims · 8 setups
Accounting for variation in ribosome footprint lengths, by aligning footprints to the correct end, reveals the ribosome A and P site locations.
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Protein length in eukaryotic and prokaryotic proteomes.
PMID 15951512 · PMC1150220 · Nucleic acids research · 2005 · 7 claims · 5 setups
Eukaryotic proteins are significantly longer than prokaryotic proteins across virtually all functional categories and the majority of protein families
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A focused antibody library for selecting scFvs expressed at high levels in the cytoplasm.
PMID 18034894 · PMC2241821 · BMC biotechnology · 2007 · 7 claims · 7 setups
A human scFv library was built on the single scFv13R4 framework with CDR3 loops diversified to mimic natural human CDR3 amino-acid distributions.
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Genetic analysis of Mycobacterium abscessus reveals genomic diversity linked to global plasmid distribution.
PMID 41858613 · PMC12995706 · iScience · 2026 · 8 claims · 8 setups
Three novel plasmids (pMAB625-1, pMAB625-2, pMAB625-3) were identified in M. abscessus isolates Abs1-5, absent from type strain ATCC 19977.
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Has reproduction · 64
metaGEM: reconstruction of genome scale metabolic models directly from metagenomes.
PMID 34614189 · PMC8643649 · Nucleic acids research · 2021 · 8 claims · 8 setups
metaGEM enables end-to-end reconstruction of FBA-ready GEMs directly from metagenomes without relying on reference genomes
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Proteomics in alcohol research.
PMID 12875051 · PMC6683837 · Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism · 2002 · 7 claims · 8 setups
The proteome is larger and more complex than the genome due to differential splicing, post-translational modifications (PTMs), and protein-protein interactions.
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From genomes to systems.
PMID 15535877 · PMC545775 · Genome biology · 2004 · 8 claims · 8 setups
Biological networks (protein-gene interactions in the genome, protein-protein interactions in the proteome, biochemical reactions in the metabolome) are scale-free rather than random
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Towards the identification of essential genes using targeted genome sequencing and comparative analysis.
PMID 17052348 · PMC1624830 · BMC genomics · 2006 · 8 claims · 8 setups
Phyletic retention (ortholog presence across organisms) is the single most predictive feature of gene essentiality in both E. coli and S. cerevisiae.
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Genetic microheterogeneity and phenotypic variation of Helicobacter pylori arginase in clinical isolates.
PMID 17408487 · PMC1853099 · BMC microbiology · 2007 · 8 claims · 8 setups
Arginase activity varies more than 100-fold among H. pylori clinical isolates and laboratory-adapted strains
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Pathway analysis for intracellular Porphyromonas gingivalis using a strain ATCC 33277 specific database.
PMID 19723305 · PMC2753363 · BMC microbiology · 2009 · 8 claims · 5 setups
Using the ATCC 33277-specific genome annotation improves proteome coverage (more proteins identified and more abundance ratios calculated) compared to the W83 annotation
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Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cells.
PMID 16251401 · PMC1270952 · Nucleic acids research · 2005 · 8 claims · 8 setups
ZFNs combining the FokI nuclease domain with custom zinc finger proteins can deliver site-specific double-strand breaks to plant and mammalian genomes.
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Has reproduction · 52
Thermophilic and mesophilic sulfate reduction by rare biosphere bacteria in acidic metal-bearing mine wastes from the temperate climate zone.
PMID 41345487 · PMC12739157 · Scientific reports · 2025 · 7 claims · 8 setups
Sulfate reduction rates (SRR) at in-situ ambient temperature in acidic Bom-Gorkhon tailings sediments are unexpectedly high, up to 9.86 µmol SO4 cm-3 day-1.