Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 53
iceDP: identifying inter-chromatin engagement via density peaks clustering algorithm.
PMID 41499218 · PMC12777978 · Briefings in bioinformatics · 2026 · 7 claims · 8 setups
iceDP is a tool that uses the Density Peaks clustering algorithm plus a distribution test and fold-change filter to identify non-homologous inter-chromatin contacts (NHCCs) from Hi-C data
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Has reproduction · 80
TP53 engagement with the genome occurs in distinct local chromatin environments via pioneer factor activity.
PMID 25391375 · PMC4315292 · Genome research · 2015 · 8 claims · 8 setups
TP53 binding events fall into three distinct categories defined by the local chromatin environment: TSS (H3K4me3+), enhancer (H3K4me1+/H3K4me3-), and distal (H3K4me1-/H3K4me3-) peaks.