Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Developmental reprogramming underlies chemotherapy resistance in favorable-histology Wilms tumor.

  PMID 41850280 · PMC13103949 · Cell reports · 2026 · 8 claims · 8 setups

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  Chemotherapy-resistant KT-47R tumors show blastemal predominance and reduced stromal content compared to pre-treatment KT-47PT

  kt-47 kt-47pt histology whole-exome cut&tag

• KLF5 controls subtype-independent highly interactive enhancers in pancreatic cancer to regulate cell survival.

  PMID 41849608 · PMC12998525 · Science advances · 2026 · 8 claims · 8 setups

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  KLF5 binds subtype-independent highly interactive enhancers in PDAC that interact with essential genes

  classical aspc1 panel l3.6pl atac-seq h3k27ac h3k4me3-anchored

• Targeting Wnt/β-catenin and circadian regulator restores PRC2/EZH2-controlled chromatin bivalency and suppresses cell state diversity.

  PMID 41842971 · PMC13132380 · The Journal of clinical investigation · 2026 · 8 claims · 8 setups

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  PRC2i/EZH2i alone or combined with AR inhibitors induce diverse cell state programs (CSPs) that increase tumor cell invasion, metastasis, and drug resistance despite only modest suppression of tumor growth.

  lncap pca pdx clinical viability tumor ic50