Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Robust transcriptomic hallmarks targeting intratumor heterogeneity in intrahepatic cholangiocarcinoma.

  PMID 41916296 · PMC13130669 · Cell reports. Medicine · 2026 · 8 claims · 8 setups

  Full-text index only

  Immune and stromal heterogeneity, rather than genetic variation, are primary drivers of gene expression ITH in iCCA

  multi-region icca four lihv bulk hallmark single-cell

• Systematic design of combination therapy by targeting master regulators of coexisting diffuse midline glioma cell states.

  PMID 42020604 · PMC13175895 · Nature genetics · 2026 · 8 claims · 6 setups

  Full-text index only

  A generalizable, network-based framework was established to systematically identify combination therapies targeting complementary coexisting tumor cell states

  malignant eight patient-derived dmg single-cell pooled plate-seq

• MetaScreener: a robust dual-mode framework for directional prioritization of actionable signatures through multi-dataset and multi-approach integration.

  PMID 41845481 · PMC13107662 · Journal of translational medicine · 2026 · 8 claims · 7 setups

  Full-text index only

  MetaScreener is a dual-mode framework (DiffMetaScreener for discrete labels, CorMetaScreener for continuous variables) integrating over 4,000 analysis pipelines to compute activation/inhibition directionality indices (ADI/IDI/DI) for gene signatures

  crc independent ctrp rko differential robustness single-cell

• Single-cell transcriptomics identifies regulatory T cell heterogeneity in gestational diabetes mellitus.

  PMID 41933176 · PMC13223204 · Communications medicine · 2026 · 8 claims · 8 setups

  Full-text index only

  Treg cluster proportions do not significantly differ between GDM and healthy control patients

  sorted pbmcs treg gdm-patient single-cell mass gene

• Vaccine-induced ICOS(+)CD38(+) circulating Tfh are sensitive biosensors of age-related changes in inflammatory pathways.

  PMID 34095875 · PMC8149371 · Cell reports. Medicine · 2021 · 8 claims · 8 setups

  Has reproduction · 88

  Vaccine-induced ICOS+CD38+ cTfh from elderly adults show increased TNF-NF-κB pathway transcriptional signaling compared to young adults at day 7 post-vaccination

  pbmc sorted rna-seq icos+cd38+ flow bulk gene

• Emergent dynamics of underlying regulatory network links EMT and androgen receptor-dependent resistance in prostate cancer.

  PMID 36851919 · PMC9957767 · Computational and structural biotechnology journal · 2023 · 8 claims · 7 setups

  Has reproduction · 78

  Simulations of the EMT-AR crosstalk network reveal four possible phenotypes: epithelial-sensitive (ES), epithelial-resistant (ER), mesenchymal-resistant (MR), and mesenchymal-sensitive (MS), with MS occurring rarely

  gene racipe clinical tcga racipe influence principal