Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• DNA Methylation Directs Polycomb-Dependent 3D Genome Re-organization in Naive Pluripotency.

  PMID 31722211 · PMC6856714 · Cell reports · 2019 · 7 claims · 6 setups

  Has reproduction · 50

  The altered 3D genome of 2i-cultured ESCs (chromatin decompaction and loss of polycomb interactions at polycomb targets) is due to redistribution of polycomb away from its targets.

  ring1b− e3.5 e14 3b3l fluorescence fish situ

• An epigenomic investigation of atrial fibrillation in a matched left and right atrial human cohort.

  PMID 41906156 · PMC13045105 · Clinical epigenetics · 2026 · 8 claims · 6 setups

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  H3K27ac epigenomic profiles differ more strongly by anatomical side (left vs right atrium) than by disease status (AF vs SR)

  left independent paired ipsc-derived h3k27ac bulk rt-qpcr

• pmid-42100854

  PMID 42100854 · PMC13229940 · 8 claims · 6 setups

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  SCEG-HiC, a weighted graphical lasso (wglasso) method, predicts enhancer-gene links from single-cell multi-omics data by integrating bulk average Hi-C as a prior penalty matrix

  specified covid-19 scatac scatac-seq bulk

• STAG2 loss amplifies EWS-FLI1-driven microsatellite enhancer activity promoting Ewing sarcoma aggressiveness.

  PMID 41950086 · PMC13079922 · Proceedings of the National Academy of Sciences of the United States of America · 2026 · 8 claims · 8 setups

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  STAG2 loss does not globally attenuate EWS-FLI1 activity but reprograms its chromatin binding, redirecting it from short (1-4x) GGAA-repeat sites toward long/multimeric (≥5x) GGAA-repeat microsatellite enhancers

  a673 tc-71 chip-seq immunoblot atac-seq