Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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GeneKeyDB: a lightweight, gene-centric, relational database to support data mining environments.
PMID 15790402 · PMC1274265 · BMC bioinformatics · 2005 · 8 claims · 6 setups
GeneKeyDB is a lightweight, gene-centric relational database that supports data mining and integration with computational analysis tools.
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RotaC: a web-based tool for the complete genome classification of group A rotaviruses.
PMID 19930627 · PMC2785824 · BMC microbiology · 2009 · 7 claims · 4 setups
RotaC is a freely available web-based tool for complete genome classification of group A rotaviruses across all 11 gene segments.
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Has reproduction · 68
Cell-type annotation with accurate unseen cell-type identification using multiple references.
PMID 37379341 · PMC10335708 · PLoS computational biology · 2023 · 8 claims · 4 setups
mtANN integrates multiple reference datasets and eight gene selection methods via ensemble learning (multiple deep classification models + majority voting) to improve cell-type annotation accuracy
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RAId_DbS: mass-spectrometry based peptide identification web server with knowledge integration.
PMID 18954448 · PMC2605478 · BMC genomics · 2008 · 7 claims · 4 setups
Constructed enhanced protein databases integrating annotated SAPs, PTMs, and disease associations for 17 organisms.
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Natural history of S-adenosylmethionine-binding proteins.
PMID 16225687 · PMC1282579 · BMC structural biology · 2005 · 8 claims · 6 setups
The last universal common ancestor (LUCA) of cellular life had between 10 and 20 SAM-binding proteins from at least 5 fold classes
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Has reproduction · 60
TRAPID 2.0: a web application for taxonomic and functional analysis of de novo transcriptomes.
PMID 34197621 · PMC8464036 · Nucleic acids research · 2021 · 8 claims · 8 setups
TRAPID 2.0 is a web application performing global characterization of de novo transcriptomes via structural, functional, and taxonomic annotation in an initial processing phase, followed by an exploratory phase of downstream analyses.
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ProMiR II: a web server for the probabilistic prediction of clustered, nonclustered, conserved and nonconserved microRNAs.
PMID 16845048 · PMC1538778 · Nucleic acids research · 2006 · 6 claims · 4 setups
ProMiR II improves on the original ProMiR by integrating free energy, G/C ratio, conservation score and entropy for more controllable miRNA prediction
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Analysis of the human Alu Ye lineage.
PMID 15725352 · PMC554112 · BMC evolutionary biology · 2005 · 8 claims · 6 setups
Two new Alu subfamilies, Ye4 and Ye6, were discovered, complementing the previously described Ye5 subfamily.
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miRGen 2.0: a database of microRNA genomic information and regulation.
PMID 19850714 · PMC2808909 · Nucleic acids research · 2010 · 7 claims · 6 setups
miRGen 2.0 is a database providing comprehensive information about the genomic position of human and mouse microRNA coding transcripts and their regulation by transcription factors
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Has reproduction
D2H2: diabetes data and hypothesis hub.
PMID 38107655 · PMC10723036 · Bioinformatics advances · 2023 · 6 claims · 5 setups
D2H2 is a web portal hosting hundreds of curated, uniformly reprocessed diabetes-relevant transcriptomics datasets from GEO with per-study visualization, differential expression, and single-gene queries.
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A genome-wide survey of segmental duplications that mediate common human genetic variation of chromosomal architecture.
PMID 15588494 · PMC3525102 · Human genomics · 2004 · 8 claims · 5 setups
PSD-mediated genomic architecture analogous to the 8p23/4p16 inversion regions is not unique to those loci but recurs genome-wide.
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SPSmart: adapting population based SNP genotype databases for fast and comprehensive web access.
PMID 18847484 · PMC2576268 · BMC bioinformatics · 2008 · 7 claims · 8 setups
SPSmart is a novel tool for accessing and combining large-scale SNP genotype databases with population information
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FGF: a web tool for Fishing Gene Family in a whole genome database.
PMID 17584790 · PMC1933194 · Nucleic acids research · 2007 · 6 claims · 3 setups
FGF efficiently searches and identifies gene families in whole-genome databases and outputs visual phylogenetic trees annotated with gene structure, chromosome position, duplication fate, and selective pressure (Ka/Ks)
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L1Base: from functional annotation to prediction of active LINE-1 elements.
PMID 15608246 · PMC539998 · Nucleic acids research · 2005 · 7 claims · 6 setups
L1Base is a database of putatively active LINE-1 insertions in human, mouse and rat genomes, containing FLI-L1s (intact in both ORFs), ORF2-L1s (intact ORF2, disrupted ORF1), and FLnI-L1s (full-length, >6000 bp, non-intact)
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NovelFam3000--uncharacterized human protein domains conserved across model organisms.
PMID 16533400 · PMC1440326 · BMC genomics · 2006 · 8 claims · 7 setups
NovelFam3000 is an online data centre unifying bioinformatics resource links, news, comments, and user-submitted experimental data (including a Gene Characterization Index) for ~3000 uncharacterized Pfam-B/DUF domain families conserved across worm, fly, and human