Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 9

System / cell line: term ✕ Assay: imaging ✕ Clear

Precancerous niche remodelling dictates nascent tumour persistence.

PMID 41781610 · PMC13148994 · Nature · 2026 · 8 claims · 8 setups

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Newly emerging tumours actively remodel their surrounding stroma into a 'precancerous niche' that determines their long-term survival.

upper nascent oesophagus carcinogen-free immunofluorescence edu immune
Anti-CSF-1R therapy with combined immuno-chemotherapy coordinate an adaptive immune response to eliminate macrophage enriched triple negative breast cancers.

PMID 41484081 · PMC12858953 · Nature communications · 2026 · 8 claims · 8 setups

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Combined low-dose CTX + anti-CSF-1R (SNDX-ms6352) is highly effective against aggressive metastatic Trp53-null TNBC models with high macrophage infiltration, producing complete tumor regression in claudin-low models.

trp53-null complete t12 cell-deficient imaging survival tumor
TGFβ induces an atypical EMT to evade immune mechanosurveillance in lung adenocarcinoma dormant metastasis.

PMID 41492090 · PMC12858408 · Nature cancer · 2026 · 7 claims · 8 setups

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TGFβ initially induces a full, typical EMT (stress fibers, loss of epithelial markers, motility) in dormancy-competent LUAD progenitors that subsequently transitions into an atypical spheroidal mesenchymal state lacking actin stress fibers.

h2087-lcc m802t4-lcc reconstructed immunofluorescence antibody-mediated
Small molecule-directed differentiation of submerged-cultured human nasal airway epithelia for respiratory disease modeling.

PMID 41875894 · PMC13130688 · Cell reports. Medicine · 2026 · 8 claims · 7 setups

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Combined DAPT (Notch/γ-secretase inhibitor) and DMH1 (BMP inhibitor) treatment induces mucociliary differentiation of submerged nasal basal cell cultures on conventional plasticware

cryopreserved nasal s-diff basal immunofluorescence quantitative single-cell
GLYATL1 is associated with metabolic and epigenetic changes and with endocrine resistance in luminal breast cancer.

PMID 42050691 · PMC13126711 · Clinical epigenetics · 2026 · 8 claims · 8 setups

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GLYATL1 expression is upregulated in AI-resistant breast cancer cell models and in patients undergoing AI therapy

mcf7 lysates rna-sequencing atac-sequencing epic
CASK loss of function differentially regulates neuronal maturation and synaptic function in human induced cortical excitatory neurons.

PMID 36262316 · PMC9574418 · iScience · 2022 · 7 claims · 8 setups

Has reproduction · 62

Immature (day 7) CASK KO induced neurons show increased dendritic complexity/neurite overgrowth and upregulated gene networks for cell adhesion, neurite outgrowth, and cytoskeletal organization.

day mature bulk qrt-pcr gene
Vascular adhesion protein-1 defines a unique subpopulation of human hematopoietic stem cells and regulates their proliferation.

PMID 34719737 · PMC8629906 · Cellular and molecular life sciences : CMLS · 2021 · 7 claims · 8 setups

Has reproduction · 50

VAP-1 is expressed on a subset of human HSC and on bone marrow vasculature forming a hematogenic niche

bone sorted cord femur flow bulk single-cell
Single-cell transcriptomics identifies Keap1-Nrf2 regulated collective invasion in a Drosophila tumor model.

PMID 36321803 · PMC9708074 · eLife · 2022 · 7 claims · 5 setups

Has reproduction · 72

Follicle cell-specific Lgl knockdown (Lgl-KD) causes loss of apical-basal polarity and invasive multilayering of the follicular epithelium without long-distance metastasis

drosophila single-cell bulk immunofluorescence
Vitamin C Conditioning Generates Tumor-Targeting CAR T Cells with Superior Cytotoxicity and Fitness in a Posttransplant Lymphoproliferative Disorder Tumor Model.

PMID 41416402 · PMC13136873 · Molecular cancer therapeutics · 2026 · 8 claims · 8 setups

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VitC conditioning enhances transduction efficiency and proliferative capacity, yielding a higher yield of CD4+ and CD8+ CAR19-Ts

cd3+ je6-1 car19-ts coculture flow nf-κb cytotoxicity

Experiments

Precancerous niche remodelling dictates nascent tumour persistence.

Anti-CSF-1R therapy with combined immuno-chemotherapy coordinate an adaptive immune response to eliminate macrophage enriched triple negative breast cancers.

TGFβ induces an atypical EMT to evade immune mechanosurveillance in lung adenocarcinoma dormant metastasis.

Small molecule-directed differentiation of submerged-cultured human nasal airway epithelia for respiratory disease modeling.

GLYATL1 is associated with metabolic and epigenetic changes and with endocrine resistance in luminal breast cancer.

CASK loss of function differentially regulates neuronal maturation and synaptic function in human induced cortical excitatory neurons.

Vascular adhesion protein-1 defines a unique subpopulation of human hematopoietic stem cells and regulates their proliferation.

Single-cell transcriptomics identifies Keap1-Nrf2 regulated collective invasion in a Drosophila tumor model.

Vitamin C Conditioning Generates Tumor-Targeting CAR T Cells with Superior Cytotoxicity and Fitness in a Posttransplant Lymphoproliferative Disorder Tumor Model.