Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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LBR and LAP2 mediate heterochromatin tethering to the nuclear periphery to preserve genome homeostasis.
PMID 41735607 · PMC12992122 · Nature cell biology · 2026 · 7 claims · 8 setups
Combined downregulation of 12 abundant, ubiquitously expressed nuclear envelope proteins (si-11) causes global detachment of constitutive heterochromatin from the nuclear envelope and its relocation to the nuclear interior in multiple mammalian cell types