Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Global sequencing of proteolytic cleavage sites in apoptosis by specific labeling of protein N termini.

  PMID 18722006 · PMC2566540 · Cell · 2008 · 7 claims · 8 setups

  Full-text index only

  A subtiligase-based N-terminal biotinylation and enrichment method enables global identification and sequencing of protease cleavage sites in complex mixtures

  jurkat computational immunoblotting structural protein-protein

• SMARCB1 missense mutants disrupt SWI/SNF complex stability and remodeling activity.

  PMID 41951591 · PMC13237135 · Nature communications · 2026 · 8 claims · 8 setups

  Full-text index only

  RPT2 domain missense mutations disrupt SMARCB1 antiproliferative function by destabilizing the SWI/SNF complex and impairing chromatin remodeling and transcriptional regulation, comparable to nonsense mutations

  g401 smarcb1 cohorts proliferation-based inducible immunoblot

• Nitrosothiol reactivity profiling identifies S-nitrosylated proteins with unexpected stability.

  PMID 19101475 · PMC2628636 · Chemistry & biology · 2008 · 8 claims · 7 setups

  Full-text index only

  Most protein nitrosothiols are rapidly denitrosylated by physiological GSH, but a small subset show markedly reduced GSH reactivity and remain stably S-nitrosylated

  brain hemoglobin crystal send.1 biotin chemical snocap