Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Lactate and histone H3K18 lactylation are associated with metabolic control of gene expression in the retina.

  PMID 41950290 · PMC13095125 · PLoS genetics · 2026 · 8 claims · 8 setups

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  Enhanced ATP production during mouse retinal development is achieved primarily through an increase in glycolysis rather than mitochondrial respiration.

  retina histones histone retinal seahorse lactate-glo ldh

• Understanding the function of Pax5 in development of docetaxel-resistant neuroendocrine-like prostate cancers.

  PMID 39183332 · PMC11345443 · Cell death & disease · 2024 · 7 claims · 8 setups

  Has reproduction · 69

  Pax5 is an important transcription factor driving neuronal gene expression and is specific to t-NEPC

  ne-like prostate lucap mcrpc atac-seq acetylated-histone rna-seq

• Cancer-predicting transcriptomic and epigenetic signatures revealed for ulcerative colitis in patient-derived epithelial organoids.

  PMID 29983891 · PMC6033374 · Oncotarget · 2018 · 7 claims · 6 setups

  Has reproduction · 65

  UC patient-derived organoids histologically phenocopy primary UC tissue, showing disorganized stratified epithelium, reduced mucin/goblet cells, and non-uniform proliferation compared to non-IBD organoids

  patient-derived h3k27ac rna-seq chip-seq histology

• Developmental reprogramming underlies chemotherapy resistance in favorable-histology Wilms tumor.

  PMID 41850280 · PMC13103949 · Cell reports · 2026 · 8 claims · 8 setups

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  Chemotherapy-resistant KT-47R tumors show blastemal predominance and reduced stromal content compared to pre-treatment KT-47PT

  kt-47 kt-47pt histology whole-exome cut&tag