Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Toward stem cell systems biology: from molecules to networks and landscapes.
PMID 19329576 · PMC2738746 · Cold Spring Harbor symposia on quantitative biology · 2008 · 7 claims · 6 setups
Stem-cell-fate specification is an extremely complex process regulated by multiple mutually interacting molecular mechanisms with numerous regulatory feedback loops.
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Has reproduction · 74
ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia.
PMID 22955991 · PMC3431496 · Genome research · 2012 · 8 claims · 8 setups
ENCODE/modENCODE define a set of working standards and guidelines for ChIP-seq covering antibody validation, experimental replication, sequencing depth, data/metadata reporting, and data quality assessment.
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Has reproduction · 76
PI3K inhibitors protect against glucocorticoid-induced skin atrophy.
PMID 30737086 · PMC6441871 · EBioMedicine · 2019 · 7 claims · 8 setups
PI3K/mTOR/Akt inhibitors are a pharmacological class that represses glucocorticoid-induced REDD1 and FKBP51 expression, identified via LINCS drug-repurposing screen.
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An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets.
PMID 14519204 · PMC328458 · Genome biology · 2003 · 8 claims · 6 setups
The Myc Target Gene database integrates literature evidence to prioritize candidate Myc-responsive genes and cluster them into functional groups
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Has reproduction · 61
Multi-omics analyses identify mannose phosphate isomerase-centered hypoxia-induced angiogenesis signature in colorectal cancer.
PMID 41204349 · PMC12595641 · Journal of translational medicine · 2025 · 8 claims · 8 setups
Twelve HIA-related genes were identified that are transcriptionally activated by HIFs and functionally implicated in angiogenesis in CRC.
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Neuroscience in the era of functional genomics and systems biology.
PMID 19829370 · PMC3645852 · Nature · 2009 · 8 claims · 7 setups
Omics/discovery-based approaches do not eschew hypotheses but elevate hypothesis testing to high-throughput hypothesis generation and prioritization.