Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• A pan-cancer single-cell transcriptomic atlas of human bone metastases.

  PMID 41619722 · PMC12923970 · Cell reports. Medicine · 2026 · 8 claims · 8 setups

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  Constructed a pan-cancer single-cell transcriptomic atlas of 62 human bone metastases (predominantly spinal) across 13 primary cancer types, with paired primary tumor and normal bone marrow samples.

  bone paired plasmacytoma malignant scrna-seq ihc infercnv

• Longitudinal Profiling of Tumor and Immune Compartments Uncovers Patterns of Dysregulation and Associations with Response in Multiple Myeloma.

  PMID 41364805 · PMC13012255 · Blood cancer discovery · 2026 · 7 claims · 8 setups

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  IFN-γ signaling after autologous stem cell transplant (ASCT) is associated with markers of impaired CD8+ T-cell memory phenotype

  cd138neg cd138pos bone cd8+ single-cell bulk whole-genome

• Benchmarking RNA velocity methods across 17 independent studies.

  PMID 41916302 · PMC13106975 · Cell reports methods · 2026 · 8 claims · 6 setups

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  No single RNA velocity method exhibited superior performance across all accuracy, stability, and usability assessments

  scrna-seq same representative dyngen-simulated velocity cross-method downsampling

• Cell type-specific network analysis in Diversity Outbred mice identifies genes potentially responsible for human bone mineral density GWAS associations.

  PMID 41811178 · PMC12978698 · eLife · 2026 · 8 claims · 8 setups

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  Cell type-specific Bayesian and co-expression networks generated from BMSC-OB scRNA-seq data in Diversity Outbred mice can prioritize and contextualize genes underlying human BMD GWAS associations

  bmsc-ob genes mesenchymal gtex scrna-seq cellect iterativewgcna

• Single-cell analysis reveals multi-faceted features of B cell development, together with age-associated B cell subpopulations.

  PMID 41520091 · PMC12905261 · Communications biology · 2026 · 8 claims · 8 setups

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  18 B cell subpopulations were identified spanning the full developmental continuum from early progenitors to plasma cells, including 4 previously unappreciated minor subpopulations (FTLhi, S100A8hi immature; FOShi, HSPA1Ahi naïve).

  in-house enriched tonsil peripheral scrna-seq scvdj-seq velocity

• Dynamic changes of the immune microenvironment in ovarian cancer following neoadjuvant chemotherapy.

  PMID 41872134 · PMC13039919 · Cell death discovery · 2026 · 8 claims · 8 setups

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  Prostaglandin-mediated immunosuppressive microenvironment formation is a critical contributor to chemotherapy resistance following cisplatin treatment

  high-grade hgsoc bone bmdms scrna-seq cell-cell tensor

• Interpretable learning of temporal cellular dynamics from single-cell data.

  PMID 41875867 · PMC13030976 · Cell reports methods · 2026 · 7 claims · 7 setups

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  NeuroVelo couples a linear latent phase-space projection with a non-linear neural ODE, using RNA velocity as a physics-informed loss penalty, to jointly model cellular dynamics and enable gene-level interpretability

  gastrulation bone pancreatic cancer scrna-seq chip-seq computational

• Benchmarking component choices for unpaired single cell RNA and epigenomic integration.

  PMID 41987329 · PMC13192178 · Genome biology · 2026 · 7 claims · 8 setups

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  Gene activity scores (GAS) show limited correlation with actual gene expression but effectively preserve cellular neighborhood structure and support clustering.

  e18 pbmc brain kidney scrna-seq share-seq gas