Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
-
Full-text index only
Tensor-cell2cell v2 unravels coordinated dynamics of protein- and metabolite-mediated cell-cell communication.
PMID 41719185 · PMC12937581 · Bioinformatics (Oxford, England) · 2026 · 8 claims · 4 setups
Tensor-cell2cell v2 implements a non-negative coupled tensor component analysis (CTCA) that jointly factorizes protein- and metabolite-mediated communication tensors sharing context, sender, and receiver dimensions while keeping ligand-type-specific (private) dimensions separate.
-
Has reproduction · 52
Social complexity, life-history and lineage influence the molecular basis of castes in vespid wasps.
PMID 36828829 · PMC9958023 · Nature communications · 2023 · 8 claims · 7 setups
A shared genetic toolkit of caste-associated genes exists across vespid wasp species spanning different levels of social complexity
-
Full-text index only
Single cell profiling reveals malignant states and immune landscapes in PCNSL and systemic DLBCL.
PMID 42023148 · PMC13097095 · iScience · 2026 · 8 claims · 8 setups
PCNSL and sDLBCL contain five distinct malignant B-cell subtypes (B0-B4) with discrete differentiation trajectories
-
Full-text index only
Distinct origins and niches determine the cellular responsiveness of CNS macrophages after repopulation.
PMID 41851525 · PMC13132723 · Nature immunology · 2026 · 8 claims · 8 setups
Microglia repopulate rapidly and exclusively cell-autonomously from surviving microglia after CSF-1R inhibitor (BLZ945) depletion.
-
Has reproduction · 64
Celline: a flexible tool for one-step retrieval and integrative analysis of public single-cell RNA sequencing data.
PMID 41458999 · PMC12738925 · Frontiers in bioinformatics · 2025 · 8 claims · 6 setups
Celline is a Python package that automates the full scRNA-seq workflow (retrieval, metadata extraction, preprocessing, cell-type annotation, batch correction, trajectory inference) via single-line commands.
-
Full-text index only
Differential neuronal survival defines a novel axis of sexual dimorphism in the Drosophila brain.
PMID 41529688 · PMC7618834 · Cell genomics · 2026 · 8 claims · 7 setups
Sex differences in the Drosophila central brain do not result from large-scale transcriptional reprogramming, but from selective modifications within shared developmental lineages mediated by dsx and fru.
-
Has reproduction · 70
Spatial transcriptomics reveals the molecular signatures of prodromal and advanced α-synucleinopathy.
PMID 41736854 · PMC12927100 · iScience · 2026 · 7 claims · 6 setups
Early-stage (prodromal) aSyn pathology in M83+/+ mouse brainstem is associated with upregulation of ATP/energy metabolism pathways (glycolysis, oxidative phosphorylation, fatty acid metabolism)
-
Full-text index only
Of brain and bone: the unusual case of Dr. A.
PMID 20183548 · PMC2997763 · Neurocase · 2009 · 7 claims · 8 setups
Dr. A's EXT2 mutation may play a role in the pattern of neurodegeneration seen in his FTD, given that Ext1-knockout mice show CNS defects including loss of olfactory bulbs and abnormally small cerebral cortex
-
Full-text index only
Benchmarking component choices for unpaired single cell RNA and epigenomic integration.
PMID 41987329 · PMC13192178 · Genome biology · 2026 · 7 claims · 8 setups
Gene activity scores (GAS) show limited correlation with actual gene expression but effectively preserve cellular neighborhood structure and support clustering.
-
Full-text index only
Benchmarking tools for deciphering cellular crosstalk in spatially-resolved transcriptomics.
PMID 41952215 · PMC13174004 · Genome biology · 2026 · 8 claims · 5 setups
No prior systematic, quantitative benchmark exists for CCI inference methods specifically developed for spatial transcriptomics across multiple platforms
-
Full-text index only
Structural and functional divergence of two fish aquaporin-1 water channels following teleost-specific gene duplication.
PMID 18811940 · PMC2564943 · BMC evolutionary biology · 2008 · 8 claims · 8 setups
Teleosts, unlike tetrapods, possess two closely linked paralogous AQP1 genes, aqp1a and aqp1b (formerly AQP1o), arising from a teleost-specific duplication of an ancestral AQP1 gene
-
Full-text index only
A pan-cancer single-cell transcriptomic atlas of human bone metastases.
PMID 41619722 · PMC12923970 · Cell reports. Medicine · 2026 · 8 claims · 8 setups
Constructed a pan-cancer single-cell transcriptomic atlas of 62 human bone metastases (predominantly spinal) across 13 primary cancer types, with paired primary tumor and normal bone marrow samples.
-
Full-text index only
Integrative CSF profiling identifies disease-specific immune responses in leptomeningeal disease.
PMID 41794040 · PMC13006398 · Cell reports. Medicine · 2026 · 8 claims · 8 setups
CSF exhibits distinct, disease-specific immune landscapes across CNSL, BrMs, and GB-associated LMD
-
Full-text index only
Single-cell spatial transcriptomics reveals tumor microenvironment heterogeneity in primary and lymph node-metastatic small cell lung cancer.
PMID 41916294 · PMC13130650 · Cell reports. Medicine · 2026 · 8 claims · 8 setups
Three malignant subclusters (C5, C6, C9) are enriched in LNM tumors and display distinct metabolic and angiogenic programs alongside spatial immune exclusion
-
Full-text index only
Highlights of international conference of immunogenomics and immunomics, October 8-12, 2006 Budapest, Hungary.
PMID 17470366 · PMC7130317 · Cellular immunology · 2006 · 8 claims · 8 setups
An 'immunological constant of rejection' involving interferon-stimulated genes (ISGs) and innate immune effector functions (IEF) underlies diverse immune-mediated tissue destruction processes (allograft rejection, cancer rejection, autoimmunity, infection)