Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Stimulation to secrete insulin induces pancreatic β-cell dysfunction through Tfe3 activation.

  PMID 41940345 · PMC13049674 · iScience · 2026 · 8 claims · 8 setups

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  Continuous glucose supplementation in mice induces Tfe3 nuclear accumulation in islet β-cells, associated with Mafa downregulation and impaired glucose tolerance

  c57bl pancreas min6 intraperitoneal immunofluorescence insulin

• Alternative polyadenylation mediated the downregulation of lysophosphatidylglycerol acyltransferase 1 in metabolic dysfunction-associated steatotic liver disease.

  PMID 41507908 · PMC12879358 · Lipids in health and disease · 2026 · 8 claims · 8 setups

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  Early hepatocyte-specific APA remodeling, characterized by 3' UTR lengthening of metabolism-related genes (especially LPGAT1), occurs in MASLD and is established before fibrosis progression

  liver hepg2 293t serum bulk single-cell oil

• Metabolic Adaptation of CD8⁺ T Cells Limits the Efficacy of Fatty Acid Oxidation Inhibition in Type 1 Diabetes.

  PMID 41800251 · PMC12965062 · International journal of biological sciences · 2026 · 8 claims · 8 setups

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  TMZ enhances mitochondrial membrane potential and suppresses fatty acid oxidation (FAO) in human T cells

  peripheral endoc-βh5 nod pancreatic mitochondrial extracellular glucose-stimulated

• TFEB deficiency attenuates mitochondrial degradation upon brown adipose tissue whitening at thermoneutrality.

  PMID 33516944 · PMC7903014 · Molecular metabolism · 2021 · 7 claims · 8 setups

  Has reproduction

  BAT whitening at thermoneutrality is associated with TFEB-dependent mitochondrial degradation.

  bat subscapular tfeb-bat-ko metabolically qrt-pcr western immunohistochemistry

• Homozygous P86S mutation of the human glucagon receptor is associated with hyperglucagonemia, alpha cell hyperplasia, and islet cell tumor.

  PMID 19657311 · PMC2767399 · Pancreas · 2009 · 8 claims · 6 setups

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  A homozygous P86S mutation in GCGR is associated with hyperglucagonemia and α cell hyperplasia in the patient

  patient's hek293 pancreatic sanger radioligand camp

• PW1(+) cells give rise to cardiac adipocytes during development and myofibroblasts following injury.

  PMID 42035143 · PMC13255232 · Stem cell research & therapy · 2026 · 8 claims · 8 setups

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  PW1+ cardiac mesenchymal cells serve as a progenitor population that gives rise to cardiac adipocytes during postnatal heart development

  heart pw1 sorted non-cardiomyocyte quantitative genetic adipogenesis

• Pancreatic tumours: molecular pathways implicated in ductal cancer are involved in ampullary but not in exocrine nonductal or endocrine tumorigenesis.

  PMID 11161385 · PMC2363700 · British journal of cancer · 2001 · 8 claims · 6 setups

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  PDC shows frequent alterations of K-ras, p53, p16 and DPC4, confirming these as the core molecular fingerprint of ductal cancer

  pancreatic same tumor pet sscp methylation-specific microsatellite