Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Single-nucleus epigenomic profiling of the adult human central nervous system unveils epigenetic memory of developmental programs.
PMID 41857393 · PMC13061643 · Nature neuroscience · 2026 · 8 claims · 6 setups
Adult spinal-cord-derived human oligodendroglia and astrocytes, but not microglia, show primed chromatin signatures at HOX loci and a putative SOX10 enhancer.
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CITED2 is a druggable epigenetic switch coupling neuronal maturation to regenerative decline.
PMID 41731079 · PMC13083982 · EMBO molecular medicine · 2026 · 8 claims · 8 setups
The transition from immature non-polarized to mature polarized DRG neurons (E12.5-E17.5) is associated with loss of gene expression signatures needed for regenerative growth competence.