Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Full-text index only
Selection of target sites for mobile DNA integration in the human genome.
PMID 17166054 · PMC1664696 · PLoS computational biology · 2006 · 8 claims · 8 setups
A comprehensive bioinformatic method was developed to annotate every base pair in the human genome for its likelihood of hosting integration by each of seven mobile DNA elements, using >200 genomic feature variables.
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Full-text index only
Predicting preferential DNA vector insertion sites: implications for functional genomics and gene therapy.
PMID 18047689 · PMC2106846 · Genome biology · 2007 · 8 claims · 6 setups
Vector insertion site preferences differ substantially between viral vectors and transposons, affecting both oncogenic risk in gene therapy and utility for functional genomics
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Has reproduction · 80
Progressive transformation of the HIV-1 reservoir cell profile over two decades of antiviral therapy.
PMID 36596305 · PMC9839361 · Cell host & microbe · 2023 · 8 claims · 7 setups
After long-term ART, intact HIV-1 proviruses are predominantly integrated in heterochromatin locations, most prominently centromeric satellite/micro-satellite DNA.
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Has reproduction
Repression of Divergent Noncoding Transcription by a Sequence-Specific Transcription Factor.
PMID 30576656 · PMC6310685 · Molecular cell · 2018 · 8 claims · 8 setups
Depletion of Rap1 induces divergent noncoding transcription at a large fraction of Rap1-regulated gene promoters