Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 6

System / cell line: monocytes ✕ Assay: interaction ✕ Clear

Single-cell landscape of piglet lung response with Actinobacillus pleuropneumoniae.

PMID 41843736 · PMC13014559 · Virulence · 2026 · 8 claims · 8 setups

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scRNA-seq of piglet lungs identified 18 cell subpopulations with distinct phenotypes in infected vs control lungs

piglet monocytes bronchoalveolar single-cell hematoxylin-and-eosin immunohistochemistry
OTMODE: an optimal transport theory-based framework for identifying differential features in single-cell multi-omics data.

PMID 41335419 · PMC12766913 · Bioinformatics (Oxford, England) · 2026 · 8 claims · 8 setups

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OTMODE, using an unbalanced Sinkhorn algorithm and Wald test, improves differential feature identification in single-cell multi-omics data

simulated classical degs naive simulated bulk real
Discovery of key regulators in classical monocyte phenotypes linked to COVID-19 severity using single-cell multi-omics sequencing.

PMID 41732268 · PMC12925236 · iScience · 2026 · 8 claims · 8 setups

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Two severity-associated classical monocyte (cMono) subtypes, IL7R+ and CD163+, exist with distinct transcriptional and epigenetic landscapes.

pbmcs pbmc classical cmono single-nucleus differential multimodal
Distinct origins and niches determine the cellular responsiveness of CNS macrophages after repopulation.

PMID 41851525 · PMC13132723 · Nature immunology · 2026 · 8 claims · 8 setups

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Microglia repopulate rapidly and exclusively cell-autonomously from surviving microglia after CSF-1R inhibitor (BLZ945) depletion.

brain cerebral cd11b+cd45int-hi leptomeninges flow confocal single-cell
Longitudinal Profiling of Tumor and Immune Compartments Uncovers Patterns of Dysregulation and Associations with Response in Multiple Myeloma.

PMID 41364805 · PMC13012255 · Blood cancer discovery · 2026 · 7 claims · 8 setups

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IFN-γ signaling after autologous stem cell transplant (ASCT) is associated with markers of impaired CD8+ T-cell memory phenotype

cd138neg cd138pos bone cd8+ single-cell bulk whole-genome
SLC25A37 as a novel therapeutic target for benign prostatic hyperplasia: integrative analyses of single-cell RNA sequencing and genome-wide association studies.

PMID 41726128 · PMC12917586 · Open medicine (Warsaw, Poland) · 2026 · 8 claims · 8 setups

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SLC25A37 is causally associated with increased BPH risk, supported by MR, Bayesian colocalization, and reverse MR analyses

prostate gwas eqtl bph single-cell mendelian bayesian

Experiments

Single-cell landscape of piglet lung response with Actinobacillus pleuropneumoniae.

OTMODE: an optimal transport theory-based framework for identifying differential features in single-cell multi-omics data.

Discovery of key regulators in classical monocyte phenotypes linked to COVID-19 severity using single-cell multi-omics sequencing.

Distinct origins and niches determine the cellular responsiveness of CNS macrophages after repopulation.

Longitudinal Profiling of Tumor and Immune Compartments Uncovers Patterns of Dysregulation and Associations with Response in Multiple Myeloma.

SLC25A37 as a novel therapeutic target for benign prostatic hyperplasia: integrative analyses of single-cell RNA sequencing and genome-wide association studies.