Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Proteomics studies reveal important information on small molecule therapeutics: a case study on plasma proteins.
PMID 18973825 · PMC7185545 · Drug discovery today · 2008 · 8 claims · 8 setups
Abundant plasma proteins (albumin, IgG, transferrin) act as 'molecular sponges' that bind and transport low molecular weight proteins/peptides and drugs, extending their half-life by preventing rapid renal clearance.
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Pathway analysis for intracellular Porphyromonas gingivalis using a strain ATCC 33277 specific database.
PMID 19723305 · PMC2753363 · BMC microbiology · 2009 · 8 claims · 5 setups
Using the ATCC 33277-specific genome annotation improves proteome coverage (more proteins identified and more abundance ratios calculated) compared to the W83 annotation
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The oxazolidinone derivative locostatin induces cytokine appeasement.
PMID 19917702 · PMC2799496 · Journal of immunology (Baltimore, Md. : 1950) · 2009 · 7 claims · 7 setups
RKIP is differentially localized (not differentially expressed) on the proteomic map after in vivo T cell recall compared to resting state
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A comprehensive proteomics and genomics analysis reveals novel transmembrane proteins in human platelets and mouse megakaryocytes including G6b-B, a novel immunoreceptor tyrosine-based inhibitory motif protein.
PMID 17186946 · PMC1860054 · Molecular & cellular proteomics : MCP · 2007 · 8 claims · 8 setups
Three complementary membrane-enrichment proteomic methods (lectin affinity, biotin/NeutrAvidin affinity, free flow electrophoresis) combined with LC-MS/MS identify 136 transmembrane proteins in human platelets, including many novel ones.
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Proteomic analysis of ovarian cancer cells reveals dynamic processes of protein secretion and shedding of extra-cellular domains.
PMID 18560578 · PMC2409963 · PloS one · 2008 · 8 claims · 6 setups
Ovarian cancer cells exhibit extensive shedding of extra-cellular domains from cell surface proteins into the extracellular milieu.
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Ectopic CD11c Drives SMAD3-Mediated Aberrant Antigen Presentation and Epithelial-Mesenchymal Transition in Esophageal Squamous Cell Carcinoma.
PMID 41799568 · PMC12963642 · Cancer communications (London, England) · 2026 · 8 claims · 13 setups
An ESCC epithelial cell subcluster with ectopic CD11c (ITGAX) expression, found in both mice and humans, exhibits concurrent impaired antigen presentation and EMT phenotypes
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Has reproduction · 50
ZAP targets aberrant mRNA transcripts encoding proteins with defective signal peptides for degradation.
PMID 41820617 · PMC13084044 · The EMBO journal · 2026 · 8 claims · 7 setups
ZAP (ZC3HAV1/PARP13) is a key component of the RAPP quality control pathway
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Acute high-dose irradiation disrupts cell adhesion and Silk-Ovarioid formation in human primary ovarian cells.
PMID 41485059 · PMC12930946 · Journal of ovarian research · 2026 · 8 claims · 6 setups
Acute 10 Gy X-ray irradiation does not significantly affect viability (ATP levels, mitochondrial dehydrogenase activity) of cPOCs and mPOCs over 7 days.
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A key role for mitochondria in endothelial signaling by plasma cysteine/cystine redox potential.
PMID 19879942 · PMC3057402 · Free radical biology & medicine · 2010 · 8 claims · 8 setups
Mitochondria are a major source of ROS in the endothelial signaling response to a more oxidized extracellular EhCySS