Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 6

System / cell line: tnfα ✕ Assay: intracellular ✕ Clear

RANKL inhibits macrophage proinflammatory Toll-like receptor 2 and 4 signaling and impairs killing of intracellular bacteria.

PMID 42177796 · PMC13198865 · ImmunoHorizons · 2026 · 8 claims · 8 setups

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Prior RANKL exposure increases intracellular Salmonella Typhimurium (STm) burden in mouse and human macrophages

bone bmdms raw-dual splenic bacterial viability sequencing
A new mRNA antigen vaccine induces potent B and T cell responses and in vivo protection against SARS-CoV-2.

PMID 41876554 · PMC13172340 · NPJ vaccines · 2026 · 8 claims · 8 setups

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The G1-C mRNA vaccine (RBD + membrane protein epitope) induces 8.2-fold higher WA1 RBD-specific IgG and 16.6-fold higher XBB.1.5 RBD-specific IgG than the RBD-only vaccine

plasma pbmcs spleen bone elisa pseudovirus intracellular
Single-cell RNA-sequencing highlights a curtailed NK cell function in convalescent COVID-19 pregnant women.

PMID 40661959 · PMC12257036 · Frontiers in immunology · 2025 · 7 claims · 5 setups

Has reproduction · 87

NK cells show a sustained reduction during active SARS-CoV-2 infection and persisting after recovery in pregnant women

pbmcs serum 14-color single-cell 13-plex
Multiomic analysis of ART-interruption cohorts identifies cell-extrinsic and -intrinsic mechanisms driving lymphocyte-mediated control of HIV rebound.

PMID 41864210 · PMC13245417 · Immunity · 2026 · 8 claims · 8 setups

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Delayed HIV rebound after ART interruption is not consistently associated with levels of intact HIV provirus across cohorts

pbmcs cd4+ cytof gag cytof intact bulk
Expansion and mobilization of virus-specific stem-like CD8 T cells in chronic viral infection after treatment with a long-acting IL-7, NT-I7.

PMID 41920738 · PMC13222646 · Cell reports · 2026 · 8 claims · 8 setups

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NT-I7 preferentially expands PD-1+TCF1+Tim-3- stem-like virus-specific CD8 T cells rather than effector/TD subsets during chronic LCMV infection

chronic chronically lcmv-specific spleen flow ki67 intracellular
Vitamin C Conditioning Generates Tumor-Targeting CAR T Cells with Superior Cytotoxicity and Fitness in a Posttransplant Lymphoproliferative Disorder Tumor Model.

PMID 41416402 · PMC13136873 · Molecular cancer therapeutics · 2026 · 8 claims · 8 setups

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VitC conditioning enhances transduction efficiency and proliferative capacity, yielding a higher yield of CD4+ and CD8+ CAR19-Ts

cd3+ je6-1 car19-ts coculture flow nf-κb cytotoxicity

Experiments

RANKL inhibits macrophage proinflammatory Toll-like receptor 2 and 4 signaling and impairs killing of intracellular bacteria.

A new mRNA antigen vaccine induces potent B and T cell responses and in vivo protection against SARS-CoV-2.

Single-cell RNA-sequencing highlights a curtailed NK cell function in convalescent COVID-19 pregnant women.

Multiomic analysis of ART-interruption cohorts identifies cell-extrinsic and -intrinsic mechanisms driving lymphocyte-mediated control of HIV rebound.

Expansion and mobilization of virus-specific stem-like CD8 T cells in chronic viral infection after treatment with a long-acting IL-7, NT-I7.

Vitamin C Conditioning Generates Tumor-Targeting CAR T Cells with Superior Cytotoxicity and Fitness in a Posttransplant Lymphoproliferative Disorder Tumor Model.