Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 85
Genomic regions and signaling pathways associated with indicator traits for feed efficiency in juvenile Atlantic salmon (Salmo salar).
PMID 33158415 · PMC7648306 · Genetics, selection, evolution : GSE · 2020 · 7 claims · 4 setups
A QTL for pre-smolt growth (weight gain) was identified on chromosome 9
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Systems biology and the host response to viral infection.
PMID 18066032 · PMC7097743 · Nature biotechnology · 2007 · 8 claims · 8 setups
Systems biology integration of 'omics data (transcriptomics, proteomics, genomics) with computational modeling is needed to fully understand virus-host interactions and identify novel antiviral targets
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Toxicoproteomics: a parallel approach to identifying biomarkers.
PMID 12940285 · PMC1241639 · Environmental health perspectives · 2003 · 8 claims · 8 setups
Combining parallel DNA microarray and proteomic analyses on the same tissues merges microarray's gene discovery power with proteomics' ability to exploit post-translational modifications for biomarker identification.
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From genomes to systems.
PMID 15535877 · PMC545775 · Genome biology · 2004 · 8 claims · 8 setups
Biological networks (protein-gene interactions in the genome, protein-protein interactions in the proteome, biochemical reactions in the metabolome) are scale-free rather than random
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Aerobic nonylphenol degradation and nitro-nonylphenol formation by microbial cultures from sediments.
PMID 20043151 · PMC2825322 · Applied microbiology and biotechnology · 2010 · 8 claims · 8 setups
Aerobic biodegradation of branched NP in polluted river sediment occurs within 8 days after a 2-day lag phase at 30°C
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One-pot shotgun quantitative mass spectrometry characterization of histones.
PMID 19764812 · PMC2798817 · Journal of proteome research · 2009 · 8 claims · 8 setups
One-pot propionylation and trypsin digestion of unfractionated bulk histones enables quantitative Bottom Up MS characterization of histone PTMs without prior off-line HPLC or SDS-PAGE purification
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Proteomic approaches for studying alcoholism and alcohol-induced organ damage.
PMID 23584750 · PMC3860448 · Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism · 2008 · 8 claims · 7 setups
Chronic alcohol abuse produces persistent changes in brain function (tolerance, dependence, craving) likely resulting from alterations in gene and protein expression
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Has reproduction · 94
Fatty acid synthesis suppresses dietary polyunsaturated fatty acid use.
PMID 38167725 · PMC10762034 · Nature communications · 2024 · 7 claims · 8 setups
FASN activity critically determines the use/incorporation of dietary PUFA into complex lipids in mice and humans
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A mouse to human search for plasma proteome changes associated with pancreatic tumor development.
PMID 18547137 · PMC2504036 · PLoS medicine · 2008 · 7 claims · 8 setups
GEM models combined with in-depth proteomic analysis provide a useful strategy to identify candidate cancer markers applicable to human disease with potential for early detection
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Defining the proteome.
PMID 16356278 · PMC1414090 · Genome biology · 2005 · 8 claims · 8 setups
Integration of multi-omics data is an important step toward a systems-biology approach to the proteome