Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Global proteome analysis of Leptospira interrogans.

  PMID 19663501 · PMC2757032 · Journal of proteome research · 2009 · 8 claims · 5 setups

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  563 proteins were identified in L. interrogans via combined iTRAQ and 2DGE proteomic analysis

  leptospira serum liver itraq two-dimensional immunoblot

• The use of neuroproteomics in drug abuse research.

  PMID 19926406 · PMC3947580 · Drug and alcohol dependence · 2010 · 8 claims · 8 setups

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  Neuroproteomic technologies (2D-DIGE, iTRAQ, ICAT, etc.) enable identification of protein-level changes underlying effects of drugs of abuse such as amphetamine, morphine, cocaine, and alcohol.

  rodent brain postmortem sectioned 2d-dige itraq heat

• Proteomic approaches for studying alcoholism and alcohol-induced organ damage.

  PMID 23584750 · PMC3860448 · Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism · 2008 · 8 claims · 7 setups

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  Chronic alcohol abuse produces persistent changes in brain function (tolerance, dependence, craving) likely resulting from alterations in gene and protein expression

  extracts trypsin-digested more yeast two-dimensional liquid mudpit

• Proteomics of human neurodegenerative diseases.

  PMID 18800015 · PMC2710115 · Journal of neuropathology and experimental neurology · 2008 · 8 claims · 8 setups

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  Proteomic techniques applied to autopsy brain and CSF from patients with neurodegenerative diseases provide insight into pathogenesis and enable biomarker discovery

  detergent-extractable thioflavin-s-stained tau-2-immunostained snca-immunoreactive 2-dimensional laser lc-ms-ms

• Comparing cellular proteomes by mass spectrometry.

  PMID 19886975 · PMC2784314 · Genome biology · 2009 · 8 claims · 6 setups

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  MS-based proteomics combined with cryo-electron tomography (CET) enables determination of absolute and relative protein abundances and localization

  leptospira saccharomyces specified shotgun selected cryo-electron

• Use of proteomics for validation of the isolation process of clotting factor IX from human plasma.

  PMID 19819359 · PMC2818390 · Journal of proteomics · 2010 · 8 claims · 8 setups

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  Proteomic techniques (LC-MS/MS, iTRAQ, immunochemical/biochemical methods) can monitor and validate each production step of pd F IX isolation

  plasma in-process chromatographic one-stage competitive elisa

• Proteomics technologies and challenges.

  PMID 17893073 · PMC5054093 · Genomics, proteomics & bioinformatics · 2007 · 8 claims · 8 setups

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  The proteome reflects the dynamic state of a cell, tissue, or organism more accurately than the genome, so proteomics is expected to yield better disease markers for diagnosis and therapy monitoring.

  serum myeloid formalin-fixed general maldi-tof phage maldi

• Comparative proteomics of clathrin-coated vesicles.

  PMID 17116749 · PMC2064594 · The Journal of cell biology · 2006 · 8 claims · 4 setups

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  A comparative proteomics strategy contrasting CCV fractions from control and clathrin-depleted (CHC siRNA knockdown) HeLa cells can distinguish genuine CCV proteins from copurifying contaminants

  hela western sds-page difference