Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Spatial transcriptomics identifies differentiation, lipid metabolism, and retinoid pathway alterations in acne vulgaris.
PMID 41657309 · PMC12892907 · JCI insight · 2026 · 8 claims · 6 setups
A custom KRT5-directed segmentation pipeline improves transcript assignment accuracy in the spatially complex sebaceous gland compared with standard multimodal or nuclei-expansion segmentation
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Has reproduction · 83
FAM3C/ILEI protein is elevated in psoriatic lesions and triggers psoriasiform hyperproliferation in mice.
PMID 37226685 · PMC10331587 · EMBO molecular medicine · 2023 · 8 claims · 8 setups
ILEI protein, but not mRNA, is elevated in psoriatic skin and correlates with disease severity
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Paneth cell SIRT1 deficiency increases intestinal stress resistance by modulating the gut microbiota.
PMID 41826553 · PMC13076647 · EMBO reports · 2026 · 8 claims · 8 setups
Generated a novel Paneth-cell-specific SIRT1 knockout mouse model (SIRT1 PKO, Sirt1 f/f;Defa6-Cre+)
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FOXA1 loss drives basal/squamous de-differentiation of prostate cancer and induces an immunosuppressive tumor microenvironment.
PMID 41904157 · PMC13195071 · Nature communications · 2026 · 7 claims · 8 setups
Prostate-specific Foxa1 deletion in Pten-null mice drives tumor progression by reprogramming luminal PCa cells toward a basal/squamous-like de-differentiated state