Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Novel peptide identification from tandem mass spectra using ESTs and sequence database compression.
PMID 17437027 · PMC1865584 · Molecular systems biology · 2007 · 7 claims · 6 setups
Traditional protein-sequence-database search engines fail to identify peptides from alternative splicing and coding SNP isoforms despite acquisition of good-quality tandem mass spectra
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A compatible exon-exon junction database for the identification of exon skipping events using tandem mass spectrum data.
PMID 19087293 · PMC2636810 · BMC bioinformatics · 2008 · 6 claims · 6 setups
A theoretical exon-exon junction protein database accounting for all in-phase (frame-preserving) exon combinations can be built from the Ensembl Core Database using Perl/Bioperl/MySQL/Ensembl API.
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Urinary proteomic profiling for diagnostic bladder cancer biomarkers.
PMID 19811072 · PMC3422861 · Expert review of proteomics · 2009 · 8 claims · 8 setups
Single protein biomarkers (e.g., NMP-22, BTA) suffer from high false-positive rates and none have replaced cystoscopy or cytology for bladder cancer detection.
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Has reproduction · 93
Characterization of protein isoform diversity in human umbilical vein endothelial cells via long-read proteogenomics.
PMID 36457147 · PMC9721438 · RNA biology · 2022 · 8 claims · 7 setups
Long-read RNA-seq detected 53,863 transcript isoforms from 10,426 genes in HUVECs, of which 22,195 were novel