Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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SMARCB1 missense mutants disrupt SWI/SNF complex stability and remodeling activity.
PMID 41951591 · PMC13237135 · Nature communications · 2026 · 8 claims · 8 setups
RPT2 domain missense mutations disrupt SMARCB1 antiproliferative function by destabilizing the SWI/SNF complex and impairing chromatin remodeling and transcriptional regulation, comparable to nonsense mutations
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Targeting TPX2-dependent lineage plasticity by CDK4/6 inhibition reverses therapy resistance in neuroendocrine bladder carcinoma.
PMID 41923619 · PMC13130694 · Cell reports. Medicine · 2026 · 8 claims · 8 setups
A 315-gene 'NE-like signature' (NE-like Sig), derived from the WGCNA MEmidnightblue module, marks a lineage-plasticity-associated transcriptional program distinct from canonical NE differentiation.
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Inflammatory bowel disease and mutations affecting the interleukin-10 receptor.
PMID 19890111 · PMC2787406 · The New England journal of medicine · 2009 · 8 claims · 8 setups
Homozygous loss-of-function mutations in IL10RA or IL10RB cause severe early-onset enterocolitis
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Integrative single-cell analysis uncovers distinct tumour microenvironment ecotypes and immune evasion across skin cancers.
PMID 41636115 · PMC12869349 · Clinical and translational medicine · 2026 · 7 claims · 8 setups
A malignant NARS2+NDUFC2+ melanoma cell subpopulation with reduced MHC-I expression is enriched in advanced-stage tumours and associated with worse survival and immunotherapy response.