Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• DMN-seq enriches DNA hypomethylated regions for biomarker discovery using 5-methylcytosine glycosylase.

  PMID 41673887 · PMC13097799 · Genome biology · 2026 · 8 claims · 9 setups

  Has reproduction · 80

  DMN-seq (DMN+) uses DME to nick DNA specifically at 5mC sites, enabling 5mC detection at single-base resolution via selective adaptor ligation

  synthetic partially embryonic mesc glycosylase dmn-seq ultrafast

• Single-cell exon deletion profiling reveals splicing events that shape gene expression and cell state dynamics.

  PMID 41633991 · PMC12868714 · Nature communications · 2026 · 8 claims · 5 setups

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  scCHyMErA-Seq enables simultaneous single-cell capture of Cas9 and Cas12a guide RNAs together with polyadenylated transcripts, integrating exon-deletion CRISPR screening with 10x Genomics scRNA-seq

  hap1 nrf1 flow northern droplet-based