Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 56
Analysis of subcellular transcriptomes by RNA proximity labeling with Halo-seq.
PMID 34875090 · PMC8887463 · Nucleic acids research · 2022 · 6 claims · 8 setups
Halo-seq pairs a light-activatable Halo-DBF ligand with Click chemistry to label and purify spatially defined RNA populations in living cells with high spatial specificity (~100 nm radius)
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Neuropixels Opto: combining high-resolution electrophysiology and optogenetics.
PMID 42225964 · PMC13259958 · Nature methods · 2026 · 8 claims · 7 setups
Neuropixels Opto probes integrate 960 recording sites and two sets of 14 light emitters (blue and red) on a 70-μm-wide, 1-cm-long shank via monolithic CMOS+photonics integration
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Nitrosothiol reactivity profiling identifies S-nitrosylated proteins with unexpected stability.
PMID 19101475 · PMC2628636 · Chemistry & biology · 2008 · 8 claims · 7 setups
Most protein nitrosothiols are rapidly denitrosylated by physiological GSH, but a small subset show markedly reduced GSH reactivity and remain stably S-nitrosylated