Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Agent-based modeling of cellular dynamics in adoptive cell therapy.

  PMID 41673469 · PMC13004971 · Communications biology · 2026 · 7 claims · 7 setups

  Full-text index only

  ABMACT, an agent-based model of adoptive cell therapy, recapitulated cellular dynamics in two cancer preclinical models (lymphoma and glioblastoma mouse models).

  xenograft il-15-armored cord shanley scrna-seq autonomous rechallenge

• A Novel Human Cellular System for Studying Normal Aging and for Anti-Aging Discovery.

  PMID 41556081 · PMC12816977 · Aging cell · 2026 · 6 claims · 8 setups

  Full-text index only

  In vitro hTSC-derived STBs recapitulate in vivo CTB-STB maturation and major cellular aging features, including multinucleation, hormone secretion, cell cycle arrest, genome instability, epigenetic changes, transposable element activation, and SASPs.

  peri-implantation first-trimester term-stage musc scrna-seq bulk linear

• Creation of a Single Cell RNASeq Meta-Atlas to Define Human Liver Immune Homeostasis.

  PMID 34335581 · PMC8322955 · Frontiers in immunology · 2021 · 7 claims · 8 setups

  Has reproduction · 63

  Three independently generated human liver CD45+ scRNA-seq datasets (LACEe, Lnb, LCD45e) can be co-clustered and integrated despite differing sequencing platforms and processing protocols.

  liver pbmc integrated gene scrna-seq differential ingenuity

• Cross-ancestry genome-wide association studies of liver function biomarkers uncover pleiotropic variants, systemic disease links and therapeutic targets.

  PMID 41689074 · PMC13005531 · Genome medicine · 2026 · 8 claims · 8 setups

  Full-text index only

  5,507 lead signals (P<5x10^-9) were identified for seven LFQBs across ancestries, including 210 novel loci

  hope biobank combined cross-ancestry gwas cross-ancestry functional-informed

• Gene regulatory network transitions reveal the central transcription factors in lung adenocarcinoma progression.

  PMID 41559111 · PMC12873405 · NPJ systems biology and applications · 2026 · 7 claims · 8 setups

  Full-text index only

  NR2F1 is a central transcription factor in LUAD progression, identified independently through GRN architecture transitions and gene regulation dynamics analysis

  luad epithelial myeloid nr2f1 single-cell gene binding

• Multi-modal skin atlas identifies a multicellular immune-stromal community associated with disrupted cornification and specific T cell expansion in atopic dermatitis.

  PMID 41741455 · PMC13057205 · Nature communications · 2026 · 8 claims · 8 setups

  Full-text index only

  Generated a multi-modal single-cell atlas of 280,518 cells from 27 samples/17 adults (healthy, AD non-lesional/lesional, scleroderma), integrated with 430,186 cells from four prior studies into a 710,704-cell human skin atlas with 86 annotated granular cell subsets.

  skin healthy keratinocytes re-annotated droplet-based scrna-seq bulk

• Protocol to perform cell-type-specific transcriptome-wide association study using scPrediXcan framework.

  PMID 41689808 · PMC12925207 · STAR protocols · 2026 · 6 claims · 6 setups

  Full-text index only

  scPrediXcan enables cell-type-specific transcriptome-wide association studies (TWAS) by integrating deep learning-based prediction of gene expression from DNA sequence and epigenetic features.

  acinar individual-level geuvadis beta mlp-based personalized elastic-net

• Single-nucleus multiomic profiling of the aging mouse substantia nigra reveals conserved gene alterations linked to Parkinson's disease.

  PMID 41781332 · PMC13138337 · Genome research · 2026 · 8 claims · 7 setups

  Full-text index only

  Single-nucleus multiome (RNA+ATAC) sequencing of mouse substantia nigra across four age stages (2, 6, 12, 18 months) yields a 40,125-cell atlas spanning 27 cell subclasses

  substantia allen five oligodendrocyte single-nucleus scrna-seq single-cell