Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
-
Full-text index only
A Plastic EMP1+ to LGR5+ Cell State Conversion as a Bypass to KRASG12D Pharmacologic Inhibition in Metastatic Colorectal Cancer.
PMID 41128661 · PMC12877754 · Cancer discovery · 2026 · 8 claims · 8 setups
RMC-9945 exerts durable antitumor activity in early-stage liver metastasis but has diminished therapeutic effect in advanced metastatic disease
-
Full-text index only
Podoplanin-defined tumour plasticity and CCR7-mediated lymphatic metastasis in triple-negative breast cancer.
PMID 41957138 · PMC13226698 · British journal of cancer · 2026 · 8 claims · 8 setups
A PDPN-defined tumour cell mesenchymal shift, promoted by hypoxia, is required for efficient CCR7-driven lymphatic metastasis and tumour progression
-
Has reproduction · 91
Cell fixation and preservation for droplet-based single-cell transcriptomics.
PMID 28526029 · PMC5438562 · BMC biology · 2017 · 7 claims · 8 setups
Methanol fixation stabilizes and preserves dissociated cells for weeks without compromising single-cell RNA-seq data quality
-
Has reproduction · 67
The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases.
PMID 28930663 · PMC5719893 · Immunity · 2017 · 8 claims · 8 setups
A common APOE-dependent microglial molecular signature (MGnD) — loss of homeostatic genes plus induction of inflammatory genes with Apoe among the most upregulated — occurs in ALS, MS and AD mouse models and around neuritic Aβ-plaques in human AD brain.