Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Reciprocal regulation of fibroblast-macrophage equilibrium governs skin integrity.

  PMID 41760904 · PMC13043295 · Nature immunology · 2026 · 8 claims · 8 setups

  Full-text index only

  Dpt+ fibroblasts are required to maintain skin macrophage populations in vivo; their depletion reduces CD64+ and CD11c+ macrophages

  facs-sorted skin dpt+ scrna-seq flow cellchat

• Comparative single-cell landscape of immune cells in human livers affected HBV and non-viral cirrhosis.

  PMID 41815278 · PMC12971635 · Frontiers in medicine · 2025 · 8 claims · 7 setups

  Full-text index only

  Macrophage-PLCG2 (anti-inflammatory) and CD8+ T-FABP5 subsets are expanded in HBV cirrhosis compared to non-viral cirrhosis

  liver myeloid scrna-seq spatial pathway

• In vivo induction of activin A-producing alveolar macrophages supports the progression of lung cell carcinoma.

  PMID 36650150 · PMC9845242 · Nature communications · 2023 · 8 claims · 8 setups

  Has reproduction · 96

  AMs accumulate in human lung cancer tissue and support cancer cell proliferation, contributing to unfavourable outcome

  normal llc lung c57bl immunohistochemistry count flow

• Immunoregulatory Roles of Tumor-Originated Pericytes Identified by Single-Cell Analysis in Glioblastoma.

  PMID 41001759 · PMC12713092 · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025 · 8 claims · 8 setups

  Has reproduction

  CD146 (MCAM) is a superior surface marker for sorting GBM pericytes, labeling nearly all PDGFRβ+ pericytes with strong specificity, unlike NG2 which labels fewer vessel-associated pericytes.

  facs-sorted frozen dissociated scrna-seq scrna-seq immunofluorescence fluorescence-activated

• Adhesion-Related Macrophages Regulate Metabolic Homeostasis Through CAV-1 Dependency.

  PMID 41817010 · PMC13159151 · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026 · 8 claims · 8 setups

  Full-text index only

  Adhesion-related macrophages (ARMs) are a distinct macrophage subpopulation that adheres directly to adipocytes and can be isolated using a novel vortex/bead-based method

  ewat facs-sorted arms sort-purified flow bulk atac-seq

• Airway injury induces alveolar epithelial responses mediated by macrophages.

  PMID 41579370 · PMC13090803 · Cell reports · 2026 · 8 claims · 8 setups

  Full-text index only

  Club cell injury (naphthalene) induces transient proliferation of distal AT2 progenitor cells

  lung bronchoalveolar club alveolar-enriched single-cell immunofluorescence flow

• Host-derived interleukin-1α drives tumor immunosuppression by reprogramming tumor-associated myeloid cells.

  PMID 41547846 · PMC12910057 · NPJ breast cancer · 2026 · 8 claims · 8 setups

  Full-text index only

  Deletion of host Il1α causes rejection/regression of transplanted breast tumors

  h605 pymt tumor-infiltrating two-week orthotopic flow single-cell

• ISG15-driven immune modulation and tumor progression in breast cancer metastasis: insights from single-cell and spatial transcriptomics.

  PMID 41639695 · PMC12958617 · BMC medicine · 2026 · 8 claims · 8 setups

  Full-text index only

  CSC proportion is elevated in lymph node metastatic tumor tissue (BRCA_LNMT) compared to primary tumor (BRCA_PT)

  4t1 brca tcga-brca top single-cell spatial bulk

• Mural cell-derived chemokines provide a protective niche to safeguard vascular macrophages and limit chronic inflammation.

  PMID 37652021 · PMC10588993 · Immunity · 2023 · 7 claims · 8 setups

  Has reproduction · 83

  Vascular macrophages form a spatiotemporal niche in direct contact with mural cells across microvascular and macrovascular beds

  cx3cr1-mφ rfp-rep coronary peritoneal intravital confocal single-cell

• Intestinal macrophages modulate synucleinopathy along the gut-brain axis.

  PMID 41606336 · PMC12960212 · Nature · 2026 · 8 claims · 8 setups

  Full-text index only

  ME-Macs engulf misfolded, aggregated αS and modulate αS pathology and neurodegeneration in PD mouse models

  3kl sorted me-macs snca immunohistochemistry digital mass

• Vγ1 γδ T cells steer airway macrophages toward a profibrotic response in an autochthonous lung cancer mouse model.

  PMID 41779856 · PMC12959402 · Science advances · 2026 · 7 claims · 6 setups

  Full-text index only

  Lung tumors drive expansion of both CD27+ and CD27- pulmonary γδ T cells, which acquire distinct spatial and phenotypic changes in the tumor microenvironment

  spc-cre+ microdissected sorted merged flow confocal single-cell