Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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PrimerZ: streamlined primer design for promoters, exons and human SNPs.
PMID 17537812 · PMC1933185 · Nucleic acids research · 2007 · 6 claims · 3 setups
PrimerZ automates primer design for gene promoters, exons, and human SNPs by integrating Ensembl sequence retrieval with Primer3 design in a single web workflow
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Exogean: a framework for annotating protein-coding genes in eukaryotic genomic DNA.
PMID 16925841 · PMC1810556 · Genome biology · 2006 · 8 claims · 5 setups
Exogean is a framework using directed acyclic coloured multigraphs (DACMs) to represent biological objects (mRNA, ESTs, protein alignments, exons) and iteratively combine them into complex protein-coding transcript models.
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EGASP: the human ENCODE Genome Annotation Assessment Project.
PMID 16925836 · PMC1810551 · Genome biology · 2006 · 8 claims · 6 setups
Best-performing computational gene prediction methods correctly predict at least one transcript for close to 70% of annotated genes in the ENCODE regions.
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Gene Prospector: an evidence gateway for evaluating potential susceptibility genes and interacting risk factors for human diseases.
PMID 19063745 · PMC2613935 · BMC bioinformatics · 2008 · 8 claims · 5 setups
Gene Prospector is a Web-based application that selects and prioritizes potential disease-related genes using a curated, updated literature database of genetic association studies
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Performance assessment of promoter predictions on ENCODE regions in the EGASP experiment.
PMID 16925837 · PMC1810552 · Genome biology · 2006 · 6 claims · 3 setups
Promoter predictors that combine promoter prediction with gene prediction (N-SCAN, Fprom) achieve better performance than pure ab initio promoter predictors, mainly by reducing the promoter search space and false positives
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GENCODE: producing a reference annotation for ENCODE.
PMID 16925838 · PMC1810553 · Genome biology · 2006 · 8 claims · 8 setups
GENCODE annotation combines initial manual annotation by HAVANA, experimental validation, and refinement based on results to identify protein-coding genes in ENCODE regions
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Genome sequences and great expectations.
PMID 11178275 · PMC150431 · Genome biology · 2001 · 8 claims · 3 setups
Function is known or can be predicted for an average of 62% of proteins across 31 analyzed genomes.
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Has reproduction · 83
Public Omics Explorer (POE): Enabling integrative semantic search across GEO omics datasets based on PubMed publications.
PMID 41282419 · PMC12636342 · Computational and structural biotechnology journal · 2025 · 6 claims · 4 setups
POE is a web platform that semantically links GEO datasets and ENA records through their associated PubMed publications for literature-informed dataset retrieval
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Has reproduction · 100
Smart spatial omics (S2-omics) optimizes region of interest selection to capture molecular heterogeneity in diverse tissues.
PMID 41298871 · PMC12662399 · Nature cell biology · 2025 · 7 claims · 6 setups
S2-omics is an end-to-end workflow that automatically selects ROIs from H&E histology images to maximize molecular information content for spatial omics profiling.