Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 10

System / cell line: er+ ✕ Assay: mass ✕ Clear

Contributions of proteomics to understanding phagosome maturation.

PMID 18331591 · PMC2613258 · Cellular microbiology · 2008 · 8 claims · 8 setups

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Proteomic studies across many species have identified hundreds of proteins associated with phagosomes, revealing conserved functional classes (vATPase subunits, GTPases, hydrolases, SNAREs, Rabs, cytoskeletal proteins).

macrophage dictyostelium drosophila entamoeba quantitative 2dge prefractionation
Quantitative membrane proteomics reveals new cellular targets of viral immune modulators.

PMID 17238276 · PMC1626102 · PLoS pathogens · 2006 · 8 claims · 8 setups

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SILAC-based quantitative membrane proteomics can identify novel targets of viral immunomodulators in an unbiased manner

hela silac immunoblot flow
HUPO Highlights.

PMID 19862759 · PMC4594800 · Proteomics · 2009 · 8 claims · 8 setups

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Mass spectrometry analysis of human liver reference samples (French Reference liver + Huh7 hepatoma cells) achieves substantial human genome coverage via PeptideAtlas processing

liver subcellular models fetal mass antibody-based quantitative
25th Annual San Antonio Breast Cancer Symposium, San Antonio, Texas, USA, 10-14 December 2002 Update on preclinical and translational research.

PMID 12631391 · PMC154153 · Breast cancer research : BCR · 2003 · 8 claims · 8 setups

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Growth factor signalling (EGF/HER-2/MAPK, AKT) phosphorylates the oestrogen receptor and drives development of endocrine-resistant breast cancer

xenograft serum frozen tumour xenograft mass cdna
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity.

PMID 29400713 · PMC5839993 · Nature medicine · 2018 · 8 claims · 10 setups

Has reproduction · 88

Cold adaptation increases proteasomal activity in BAT, which is required for non-shivering thermogenesis

bat body adipocytes mitochondria proteasomal core qpcr
Two-dimensional electrophoretic comparison of metastatic and non-metastatic human breast tumors using in vitro cultured epithelial cells derived from the cancer tissues.

PMID 18416831 · PMC2377273 · BMC cancer · 2008 · 6 claims · 4 setups

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Three protein spots were significantly altered in abundance between metastase-positive and metastase-negative breast cancer patient groups

excised formalin-fixed log-normalized two-dimensional liquid immunohistochemistry
Transcriptional and proteomic profiling in a cellular model of DYT1 dystonia.

PMID 19665049 · PMC2774817 · Neuroscience · 2009 · 8 claims · 7 setups

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Accumulation of mutant torsinA(ΔE) in the nuclear envelope is not sufficient to cause transcriptional dysregulation

pc6-3 hek293 microarray 2-dige mass
Nitrosative stress-induced s-glutathionylation of protein disulfide isomerase leads to activation of the unfolded protein response.

PMID 19773442 · PMC2756322 · Cancer research · 2009 · 7 claims · 8 setups

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PABA/NO treatment causes S-glutathionylation (not S-nitrosylation) of PDI in cells and in vitro

skov3 recombinant mtt daf-fm-da immunoprecipitation
Surface-enhanced laser desorption/ionization time-of-flight proteomic profiling of breast carcinomas identifies clinicopathologically relevant groups of patients similar to previously defined clusters from cDNA expression.

PMID 18510725 · PMC2481497 · Breast cancer research : BCR · 2008 · 7 claims · 7 setups

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Unsupervised hierarchical clustering of 130 SELDI-TOF peaks yielded six peak clusters and five distinct groups of breast cancer patients.

lysates breast microarrays imac-preseparated seldi-tof pilot immunohistochemistry
Tissue proteomics reveals differential and compartment-specific expression of the homologs transgelin and transgelin-2 in lung adenocarcinoma and its stroma.

PMID 19848416 · PMC2789179 · Journal of proteome research · 2009 · 6 claims · 6 setups

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Transgelin (TAGLN), transgelin-2 (TAGLN2), and cyclophilin A (PPIA) are overexpressed in lung adenocarcinoma tissue compared to matched normal lung

matched excised additional formalin-fixed 2-d lc-ms quantitative

Experiments

Contributions of proteomics to understanding phagosome maturation.

Quantitative membrane proteomics reveals new cellular targets of viral immune modulators.

HUPO Highlights.

25th Annual San Antonio Breast Cancer Symposium, San Antonio, Texas, USA, 10-14 December 2002 Update on preclinical and translational research.

Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity.

Two-dimensional electrophoretic comparison of metastatic and non-metastatic human breast tumors using in vitro cultured epithelial cells derived from the cancer tissues.

Transcriptional and proteomic profiling in a cellular model of DYT1 dystonia.

Nitrosative stress-induced s-glutathionylation of protein disulfide isomerase leads to activation of the unfolded protein response.

Surface-enhanced laser desorption/ionization time-of-flight proteomic profiling of breast carcinomas identifies clinicopathologically relevant groups of patients similar to previously defined clusters from cDNA expression.

Tissue proteomics reveals differential and compartment-specific expression of the homologs transgelin and transgelin-2 in lung adenocarcinoma and its stroma.