Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 67
NET-prism enables RNA polymerase-dedicated transcriptional interrogation at nucleotide resolution.
PMID 31156037 · PMC6693550 · RNA biology · 2019 · 8 claims · 7 setups
NET-prism, an adapted NET-seq protocol using immunoprecipitation of Pol II-associated factors, enables strand-specific, nucleotide-resolution interrogation of transcription dynamics for any Pol II-interacting protein.
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Toward stem cell systems biology: from molecules to networks and landscapes.
PMID 19329576 · PMC2738746 · Cold Spring Harbor symposia on quantitative biology · 2008 · 7 claims · 6 setups
Stem-cell-fate specification is an extremely complex process regulated by multiple mutually interacting molecular mechanisms with numerous regulatory feedback loops.
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Unraveling the histone's potential: a proteomics perspective.
PMID 18849650 · PMC2662511 · Epigenetics · 2008 · 8 claims · 8 setups
Mass spectrometry can determine the full repertoire of histone PTMs, their residue-specific location, and combinatorial patterns without requiring prior knowledge of the modification, unlike antibody-based methods
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A new era for proteomics research?
PMID 19014405 · PMC2614486 · Genome biology · 2008 · 8 claims · 8 setups
Refined mass spectrometry instrumentation and software now make whole-proteome coverage of model organisms in a single experiment conceivable
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Science star over Asia.
PMID 16149850 · PMC1201306 · PLoS biology · 2005 · 8 claims · 7 setups
Ariff Bongso and associates at Singapore's National University Hospital were the first to derive human embryonic stem cells, from a five-day-old discarded human embryo in 1994, and showed the cells were pluripotent with therapeutic transplant potential.
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Genomic and proteomic techniques applied to reproductive biology.
PMID 11574051 · PMC138959 · Genome biology · 2001 · 8 claims · 8 setups
Knockout of the E6-AP (UBE3A) gene reduces testis and prostate size in male mice and compromises estradiol action in females
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Glycomic analysis: an array of technologies.
PMID 19728746 · PMC3443568 · ACS chemical biology · 2009 · 8 claims · 8 setups
Glycosylation is the most prevalent protein post-translational modification, occurring on at least 50% of all proteins