Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Discovery of protein-protein interactions using a combination of linguistic, statistical and graphical information.
PMID 15941473 · PMC1164402 · BMC bioinformatics · 2005 · 8 claims · 5 setups
A combined linguistic+statistical+rule-based method achieves precision 0.61 and recall 0.97 (f=0.74) detecting yeast protein-protein interactions across 12,300 Medline abstracts.
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Deducing topology of protein-protein interaction networks from experimentally measured sub-networks.
PMID 18598366 · PMC2474618 · BMC bioinformatics · 2008 · 7 claims · 6 setups
Experimentally measured protein-protein interaction sub-networks are not random samples of their parent networks.
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Bacteriophage Mu integration in yeast and mammalian genomes.
PMID 18953026 · PMC2602771 · Nucleic acids research · 2008 · 8 claims · 8 setups
In vitro-assembled Mu transpososomes, delivered by electroporation, efficiently integrate marker genes into yeast, mouse ES, human HeLa, and human ES cell genomes
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Has reproduction · 55
N6-methyladenosine (m6A) reader Pho92 is recruited co-transcriptionally and couples translation to mRNA decay to promote meiotic fitness in yeast.
PMID 36422864 · PMC9731578 · eLife · 2022 · 8 claims · 8 setups
Pho92 specifically binds m6A-modified RNA via its YTH domain, both in vitro and in vivo
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Ensembl 2006.
PMID 16381931 · PMC1347495 · Nucleic acids research · 2006 · 8 claims · 5 setups
Ensembl now provides annotation for 19 genomes, up from 4 the previous year, including new mammalian (Rhesus macaque, Opossum), chordate (Ciona intestinalis), and yeast genomes.
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Proteomic approaches for studying alcoholism and alcohol-induced organ damage.
PMID 23584750 · PMC3860448 · Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism · 2008 · 8 claims · 7 setups
Chronic alcohol abuse produces persistent changes in brain function (tolerance, dependence, craving) likely resulting from alterations in gene and protein expression