Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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beta- Catenin mutations and aberrant nuclear expression during endometrial tumorigenesis.
PMID 11161379 · PMC2363713 · British journal of cancer · 2001 · 7 claims · 4 setups
Cell membrane β-catenin immunoreactivity shows a stepwise decrease from normal endometrium, through atypical hyperplasia, to grade 3 carcinoma.
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Nuclear beta-catenin expression is closely related to ulcerative growth of colorectal carcinoma.
PMID 11953860 · PMC2364167 · British journal of cancer · 2002 · 7 claims · 5 setups
Nuclear β-catenin expression is significantly associated with ulcerative growth of colorectal cancer
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Genetic changes of Wnt pathway genes are common events in metaplastic carcinomas of the breast.
PMID 18593979 · PMC3060761 · Clinical cancer research : an official journal of the American Association for Cancer Research · 2008 · 8 claims · 6 setups
Aberrant β-catenin protein expression (nuclear/cytoplasmic accumulation or reduced membrane staining) is present in nearly all metaplastic breast carcinomas, indicating Wnt pathway deregulation.
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Phylogenetic profiling of the Arabidopsis thaliana proteome: what proteins distinguish plants from other organisms?
PMID 15287975 · PMC507878 · Genome biology · 2004 · 8 claims · 6 setups
3,848 Arabidopsis proteins were identified as likely plant-specific based on phylogenetic profiling and EST confirmation in multiple plant species
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Has reproduction · 98
The butyrophilin 1a1 knockout mouse revisited: Ablation of Btn1a1 leads to concurrent cell death and renewal in the mammary epithelium during lactation.
PMID 34938960 · PMC8664049 · FASEB bioAdvances · 2021 · 8 claims · 8 setups
BTN1A1 functions as an apical membrane receptor that forms a lipid-droplet secretion complex with the redox enzyme xanthine oxidoreductase (XDH)
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System-based proteomic analysis of the interferon response in human liver cells.
PMID 15287976 · PMC507879 · Genome biology · 2004 · 7 claims · 4 setups
ICAT-based quantitative proteomics identified 1,364 proteins in Huh7 cells at <5% false-positive rate, with 54 induced and 24 repressed >2-fold by IFN treatment
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Evolution of organelle-associated protein profiling.
PMID 19110081 · PMC2680700 · Journal of proteomics · 2009 · 8 claims · 8 setups
Traditional biochemical organelle isolation followed by MS cataloguing suffers high false-positive rates because organelles cannot be purified to homogeneity and are structurally heterogeneous
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A key role for mitochondria in endothelial signaling by plasma cysteine/cystine redox potential.
PMID 19879942 · PMC3057402 · Free radical biology & medicine · 2010 · 8 claims · 8 setups
Mitochondria are a major source of ROS in the endothelial signaling response to a more oxidized extracellular EhCySS
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MAPU: Max-Planck Unified database of organellar, cellular, tissue and body fluid proteomes.
PMID 17090601 · PMC1781136 · Nucleic acids research · 2007 · 8 claims · 8 setups
MAPU is a unified, freely accessible database integrating organellar, cellular, tissue and body fluid proteomes generated by high-resolution mass spectrometry.
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Integration with the human genome of peptide sequences obtained by high-throughput mass spectrometry.
PMID 15642101 · PMC549070 · Genome biology · 2005 · 8 claims · 4 setups
PeptideAtlas, a public database integrating MS/MS-derived peptide identifications with the human genome, was built as an expandable resource for proteomic data.
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Modeling substance abuse for applications in proteomics.
PMID 20058165 · PMC3272758 · Methods in molecular biology (Clifton, N.J.) · 2009 · 8 claims · 5 setups
The intravenous self-administration paradigm models the reinforcing effects of abused drugs and allows biochemical alterations to be correlated with drug reinforcement.