Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 9

System / cell line: genome-wide ✕ Assay: mendelian ✕ Clear

Genome-wide associations of aortic distensibility suggest causality for aortic aneurysms and brain white matter hyperintensities.

PMID 35922433 · PMC9349177 · Nature communications · 2022 · 8 claims · 7 setups

Has reproduction

GWAS identified 102 genome-wide significant loci (including 27 novel) associated with aortic distensibility and area traits

same biobank arterial cardiac genome-wide multi-trait snp-based
Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome.

PMID 34561431 · PMC8463674 · Nature communications · 2021 · 8 claims · 7 setups

Has reproduction · 100

revTWMR, a reverse transcriptome-wide Mendelian Randomization approach integrating GWAS and whole-blood trans-eQTL summary statistics, is proposed to estimate the causal effect of a phenotype on gene expression.

blood ra-associated genome-wide revtwmr transcriptome-wide reverse functional
A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome.

PMID 30833571 · PMC6399342 · Nature communications · 2019 · 6 claims · 8 setups

Has reproduction · 90

A GWAS of 12,312 CTS cases and 389,344 controls in UK Biobank identifies 16 novel genome-wide significant susceptibility loci for CTS

biobank surgically gwas transformed genome-wide sequencing gene-based
Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets.

PMID 37563310 · PMC10457199 · Nature immunology · 2023 · 8 claims · 8 setups

Has reproduction · 93

Genome-wide pQTL mapping of 91 inflammation-related plasma proteins in 14,824 participants identified 180 significant pQTLs (59 cis, 121 trans) across 108 genomic regions and 70 proteins

plasma blood tissues gut genome-wide pqtl cis-eqtl
Copy number variants and common disorders: filling the gaps and exploring complexity in genome-wide association studies.

PMID 17953491 · PMC2039766 · PLoS genetics · 2007 · 8 claims · 5 setups

Full-text index only

CNVs are not easily tagged by SNPs and often fall in genomic regions poorly covered by whole-genome SNP arrays or not genotyped by HapMap, so current GWASs have largely missed their contribution to complex disorders.

genome-wide genome cohorts array-based snp bac
Ordered subsets linkage analysis of antisocial behavior in substance use disorder among participants in the Collaborative Study on the Genetics of Alcoholism.

PMID 18496835 · PMC4248599 · American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2008 · 8 claims · 5 setups

Full-text index only

Prior to OSA, modest evidence for linkage to SUD was found on chromosomes 8 and 17.

extended coga genome-wide ordered genotyping
Microsatellites and SNPs linkage analysis in a Sardinian genetic isolate confirms several essential hypertension loci previously identified in different populations.

PMID 19715579 · PMC2741446 · BMC medical genetics · 2009 · 8 claims · 6 setups

Full-text index only

Three loci (2q24, 11q23.1-25, 13q14.11-21.33) were identified by both the microsatellite and SNP genome-wide scans

talana volunteers same ogliastra genome-wide clinical genotype
Next-generation sequencing.

PMID 20030863 · PMC2797692 · Breast cancer research : BCR · 2009 · 8 claims · 7 setups

Full-text index only

Massively parallel sequencing can simultaneously capture base-pair mutations, copy number aberrations and somatic rearrangements of a cancer genome in a single experiment

individuals metastatic acute oestrogen whole-exome whole-genome large-scale
Decoding and reconstructing disease relations between dry eye and depression: a multimodal investigation comprising meta-analysis, genetic pathways and Mendelian randomization.

PMID 38548265 · PMC11954816 · Journal of advanced research · 2025 · 8 claims · 8 setups

Has reproduction · 79

Meta-analysis confirmed a positive association between DED and DEP occurrence

patients taiwan biobank twb meta-analysis genome-wide score

Experiments

Genome-wide associations of aortic distensibility suggest causality for aortic aneurysms and brain white matter hyperintensities.

Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome.

A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome.

Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets.

Copy number variants and common disorders: filling the gaps and exploring complexity in genome-wide association studies.

Ordered subsets linkage analysis of antisocial behavior in substance use disorder among participants in the Collaborative Study on the Genetics of Alcoholism.

Microsatellites and SNPs linkage analysis in a Sardinian genetic isolate confirms several essential hypertension loci previously identified in different populations.

Next-generation sequencing.

Decoding and reconstructing disease relations between dry eye and depression: a multimodal investigation comprising meta-analysis, genetic pathways and Mendelian randomization.