Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum.
PMID 19043545 · PMC2581785 · PLoS genetics · 2008 · 7 claims · 4 setups
A GWA study using serum metabolomics identifies SNPs associated with metabolite concentrations, explaining up to 12% of variance for single metabolites
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Systems biology in human health and disease.
PMID 17893698 · PMC2013921 · Molecular systems biology · 2007 · 8 claims · 5 setups
High-throughput quantitative proteomics of signaling networks (e.g., HER2 overexpression) can be correlated with biological responses like proliferation and migration to better understand pathways deregulated in cancer.
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Genomics: applications in mechanism elucidation.
PMID 19166886 · PMC2698023 · Advanced drug delivery reviews · 2009 · 8 claims · 8 setups
Genomic tools require no a priori knowledge of a compound's mode of action and can reveal biological pathways (metabolism, distribution, off-target effects) in addition to the precise mechanism of action.
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Has reproduction · 59
Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma.
PMID 33086062 · PMC7649750 · Cell reports · 2020 · 8 claims · 8 setups
KMT2D is a potent tumor suppressor in melanoma
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pmid-41501078
PMID 41501078 · PMC12780049 · 8 claims · 7 setups
MAGPIE is a computational framework (Snakemake workflow) that co-registers Visium spatial transcriptomics with MSI metabolomics and tissue morphology images from same or consecutive sections
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Genomics and proteomics of immune modulatory effects of a butanol fraction of echinacea purpurea in human dendritic cells.
PMID 18847511 · PMC2571112 · BMC genomics · 2008 · 8 claims · 8 setups
[BF/S+L/Ep] butanol fraction from E. purpurea enhances maturation of human immature dendritic cells (increased CD83 expression)